Neurology
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Randomized Controlled Trial Comparative Study Clinical Trial
Dual-task performances can be improved in patients with dementia: a randomized controlled trial.
Deficits in attention-related cognitive performance measured as dual-task performance represent early markers of dementia and are associated with motor deficits and increased risk of falling. The purpose of this study was to examine the effect of a specific dual-task training in patients with mild to moderate dementia. ⋯ This study provides Class II evidence that specific dual-task training improves dual-task performance during walking under complex S3 conditions in geriatric patients with mild to moderate dementia.
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Randomized Controlled Trial Multicenter Study
Treatment of restless legs syndrome with pregabalin: a double-blind, placebo-controlled study.
To assess the therapeutic efficacy, required dose, and tolerability of pregabalin in patients with idiopathic restless legs syndrome (RLS). ⋯ This study provides Class II evidence that pregabalin is effective for the treatment of restless legs syndrome and improves sleep architecture and periodic limb movements in placebo-unresponsive patients.