Neurology
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Multicenter Study
Ketogenic diet for adults in super-refractory status epilepticus.
To describe a case series of adult patients in the intensive care unit in super-refractory status epilepticus (SRSE; refractory status lasting 24 hours or more despite appropriate anesthetic treatment) who received treatment with the ketogenic diet (KD). ⋯ This study provides Class IV evidence that for intensive care unit patients with refractory SE, a KD leads to resolution of the SE.
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Randomized Controlled Trial Multicenter Study
ASA failure: does the combination ASA/clopidogrel confer better long-term vascular protection?
To assess whether adding clopidogrel to acetylsalicylic acid (ASA) has a long-term protective vascular effect in patients with lacunar stroke while taking ASA. ⋯ This study provides Class I evidence that for patients with recent lacunar stroke while taking ASA, adding clopidogrel as compared to continuing ASA alone does not reduce the risk of recurrent stroke.