Neurology
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Randomized Controlled Trial Multicenter Study
ASA failure: does the combination ASA/clopidogrel confer better long-term vascular protection?
To assess whether adding clopidogrel to acetylsalicylic acid (ASA) has a long-term protective vascular effect in patients with lacunar stroke while taking ASA. ⋯ This study provides Class I evidence that for patients with recent lacunar stroke while taking ASA, adding clopidogrel as compared to continuing ASA alone does not reduce the risk of recurrent stroke.