Zhonghua wei zhong bing ji jiu yi xue
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2013
Randomized Controlled Trial Comparative Study[Effects of dexmedetomidine on sedation and β-endorphin in traumatic brain injury: a comparative study with propofol].
To compare the efficacy of dextraldexmede (DEX) and propofol on sedation and β-endorphin (β-EP) in patients with moderate and severe traumatic brain injury (TBI). ⋯ The sedation efficacy of DEX was superior to propofol in moderate and severe TBI, and was able to control excessive stress response after TBI better, and with more effect on blood pressure. Plasma β-EP was elevated during the early phase of brain injury by DEX, which was considered as its positive role in the regulation of early stress.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2013
Multicenter Study[A multicenter study of respiratory multiple index in predicting weaning from mechanical ventilation in patients with acute exacerbation of chronic obstructive pulmonary disease].
To study the result of respiratory multiple index(compliance, respiratory rate, oxygenation, pressure, CROP) in predicting weaning from mechanical ventilation in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). ⋯ For the AECOPD patients received mechanical ventilation, most extubation parameter was limited. Complex parameter of CROP has higher specificity and sensitivity, and has important value in predicting extubation outcome. When CROP ≥ 13.521 ml×breath⁻¹×min⁻¹, the successful rate is high, otherwise the rate is low.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2013
Randomized Controlled Trial[The study of AutoFlow role in volume controlled ventilation].
To evaluate the efficacy and safety of automatic variable flow rate (AutoFlow) for volume control ventilation through monitoring the number of ventilator alarm. ⋯ AutoFlow is confirmed be safe for volume control ventilation mode, and could significantly reduce the alarm of ventilator.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2013
Comparative Study[Comparison of sedative effects of propofol and midazolam on emergency critical patients on mechanical ventilation].
To compare the sedative effects of propofol and midazolam, or combination of them on emergency critically ill patients on mechanical ventilation. ⋯ A combination of propofol with midazolam for emergency critically ill patients on mechanical ventilation not only can achieve a good sedative effect, reduce total amount of the drug, but also alleviate the inhibitory effect of propofol on the circulation, improve the symptoms of asynchronous ventilation, and reduce stay time in EICU.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2013
[The timing of infusion of hypertonic saline to exert protective effect on intestinal barrier function in the rabbit with intestinal ischemia/reperfusion injury].
To study the timing of infusion of hypertonic saline solution (HTS) to exert its protective effect on intestinal barrier function in rabbits with intestinal ischemia/reperfusion (I/R) injury. ⋯ HTS had the protective effect on intestine suffering from I/R injury. But the protective effect was time dependent, and early treatment shows protective effect.