Zhonghua wei zhong bing ji jiu yi xue
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Oct 2013
Randomized Controlled Trial[Effects of probiotics on blood glucose levels and clinical outcomes in patients with severe craniocerebral trauma].
To investigate the effects of probiotics on blood glucose levels and clinical outcomes in patients suffering from severe craniocerebral trauma. ⋯ Probiotics could facilitate blood glucose control in patients with severe craniocerebral injury. The underlying mechanisms and its long-term efficacy in this category of patients, however, need to be further investigated.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Aug 2013
Randomized Controlled Trial[Treatment study of hospital acquired pneumonia by optimizing dosing regimen of piperacillin/tazobactam:prolonged vs. regular infusion].
To observe the serum concentration and evaluate clinical efficacy of piperacillin/tazobactam (TZP) prolonged infusion time in treatment of hospital acquired pneumonia (HAP). ⋯ TZP prolonged the infusion time dosing regimens using in Gram negative bacteria induced by high MIC value of HAP have more stable plasma concentration, curative clinical effect and reduce the cost of treatment.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2013
Randomized Controlled Trial[The study of AutoFlow role in volume controlled ventilation].
To evaluate the efficacy and safety of automatic variable flow rate (AutoFlow) for volume control ventilation through monitoring the number of ventilator alarm. ⋯ AutoFlow is confirmed be safe for volume control ventilation mode, and could significantly reduce the alarm of ventilator.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2013
Randomized Controlled Trial Comparative Study[Effects of dexmedetomidine on sedation and β-endorphin in traumatic brain injury: a comparative study with propofol].
To compare the efficacy of dextraldexmede (DEX) and propofol on sedation and β-endorphin (β-EP) in patients with moderate and severe traumatic brain injury (TBI). ⋯ The sedation efficacy of DEX was superior to propofol in moderate and severe TBI, and was able to control excessive stress response after TBI better, and with more effect on blood pressure. Plasma β-EP was elevated during the early phase of brain injury by DEX, which was considered as its positive role in the regulation of early stress.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Apr 2013
Randomized Controlled Trial[The effect of ulinastatin on disbalance of inflammation and immune status in patients with severe sepsis].
To investigate the effect of ulinastatin (UTI) on the levels of immune regulatory cells,pro-inflammatory mediators, and the expression of human leukocyte antigen-DR (HLA-DR) in CD14⁺ monocytes. ⋯ UTI can decrease in the expression of Treg and Th17, inverse the ratio of Treg/Th17, decrease in the expression of IL-17, IL-6 and IL-10, ameliorate the immune status, and improve the expression of HLA-DR. UTI is expected to improve the prognosis of patients with severe sepsis.