Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Feb 2007
[Effect of recruitment maneuver on alveolar epithelium barrier in rat with acute lung injury].
To evaluate the influence of recruitment maneuver (RM) on alveolar epithelium barrier in rat with acute lung injury (ALI). ⋯ RM can alleviate lung tissue injury, up-regulate SP-C mRNA expression in alveolar epithelium, protect alveolar epithelium barrier and down-regulate pulmonary inflammatory mediator expression in ALI.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Feb 2007
Randomized Controlled Trial Comparative Study[An auto control comparison of the use of ProSeal laryngeal mask airway and standard laryngeal mask airway for positive pressure ventilation].
To compare the ProSeal laryngeal mask airway (PLMA) and the standard laryngeal mask airway (SLMA) for intermittent positive pressure ventilation (IPPV) in a randomized auto control design. ⋯ Compared with SLMA, PLMA can achieve a higher airway seal pressure and potentially isolate the glottis and the upper esophagus, and is safer and more effective for positive pressure ventilation.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Feb 2007
[Activation of p38 mitogen-activated protein kinase pathway in ventilator-induced lung injury in rat].
To study the activation of p38 mitogen-activated protein kinase (MAPK) and the expression of inflammatory cytokines in ventilator-induced lung injury (VILI) in rat. ⋯ Large V(T) mechanical ventilation can significantly activate the p-p38 and inflammatory cytokines, which may play an important role in VILI.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Feb 2007
[Study of the effects on the heart function when different positive end expiratory pressure levels were used on patients treated with mechanical ventilation].
To study the effects on the hemodynamics and the heart function when different positive end-expiratory pressure (PEEP) levels were used on patients treated with mechanical ventilation. ⋯ Under the condition of mechanical ventilation, when the lung volume was relatively constant, change in PEEP levels (0-13 cm H(2)O) had no obvious effects on the normal cardiac function group, but can significantly decrease right ventricular preload, PCBF and left ventricular preload. Optimal PEEP may improve the cardiac function. The change in the airway pressure is not consistent with the changes in cardiac function.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Feb 2007
[Effects of mechanical ventilation on the expression of Toll like receptor 4 in rat's alveolar macrophages].
To investigate the effects of mechanical ventilation on Toll like receptor 4 (TLR4) in rat's alveolar macrophages (AM). ⋯ Large V(T) mechanical ventilation induced injury of lungs and up-regulated TLR4 expression in rat's AM. Small V(T) mechanical ventilation avoided above-mentioned changes.