Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Feb 2007
[Effect of recruitment maneuver on alveolar epithelium barrier in rat with acute lung injury].
To evaluate the influence of recruitment maneuver (RM) on alveolar epithelium barrier in rat with acute lung injury (ALI). ⋯ RM can alleviate lung tissue injury, up-regulate SP-C mRNA expression in alveolar epithelium, protect alveolar epithelium barrier and down-regulate pulmonary inflammatory mediator expression in ALI.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Feb 2007
[Activation of p38 mitogen-activated protein kinase pathway in ventilator-induced lung injury in rat].
To study the activation of p38 mitogen-activated protein kinase (MAPK) and the expression of inflammatory cytokines in ventilator-induced lung injury (VILI) in rat. ⋯ Large V(T) mechanical ventilation can significantly activate the p-p38 and inflammatory cytokines, which may play an important role in VILI.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Feb 2007
[Study of the effects on the heart function when different positive end expiratory pressure levels were used on patients treated with mechanical ventilation].
To study the effects on the hemodynamics and the heart function when different positive end-expiratory pressure (PEEP) levels were used on patients treated with mechanical ventilation. ⋯ Under the condition of mechanical ventilation, when the lung volume was relatively constant, change in PEEP levels (0-13 cm H(2)O) had no obvious effects on the normal cardiac function group, but can significantly decrease right ventricular preload, PCBF and left ventricular preload. Optimal PEEP may improve the cardiac function. The change in the airway pressure is not consistent with the changes in cardiac function.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Feb 2007
Randomized Controlled Trial[Influence of the agents which maintain the coordination between spontaneous breathing and mechanical ventilation on haemodynamics and respiration].
To investigate the haemodynamic and respiratory changes following intravenous administration with midazolam, pavulon or both of them in the patients having incoordination between spontaneous breathing and mechanical ventilation. ⋯ The combined use of midazolam and pavulon has little influence on circulation, and it also can maintain the coordination between spontaneous breathing and mechanical ventilation. It is suggested that the combined use of midazolam and pavulon is an optimal way to improve the ventilatory function in mechanical ventilation.