Revista brasileira de anestesiologia
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Rev Bras Anestesiol · May 2017
Meta Analysis[Perioperative gabapentin and pregabalin in cardiac surgery: a systematic review and meta-analysis].
Sternotomy for cardiac surgeries causes significant postoperative pain and when not properly managed may cause significant morbidity. As neuropathic pain is a significant component here, gabapentin and pregabalin may be effective in these patients and may reduce postoperative opioid consumption. The purpose of this systematic review was to find out efficacy of gabapentin and pregabalin in acute postoperative pain after cardiac surgery. ⋯ Despite lower pain scores in the postoperative period, there is insufficient evidence to recommend routine use of gabapentin and pregabalin to reduce opioid consumption in the cardiac surgical patients.
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Rev Bras Anestesiol · Mar 2017
Meta Analysis[Effect of dexmedetomidine in children undergoing general anesthesia with sevoflurane: a meta-analysis].
Sevoflurane is often used in pediatric anesthesia and is associated with high incidence of psychomotor agitation. In such cases, dexmedetomidine (DEX) has been used, but its benefit and implications remain uncertain. We assessed the effects of DEX on agitation in children undergoing general anesthesia with sevoflurane. ⋯ Dexmedetomidine reduces psychomotor agitation during wake-up time of children undergoing general anesthesia with sevoflurane.
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Rev Bras Anestesiol · Mar 2009
Review Meta Analysis Comparative StudyNeuroaxis block compared to general anesthesia for revascularization of the lower limbs in the elderly. A systematic review with metanalysis of randomized clinical studies.
Currently, it is controversial on whether neuroaxis block (NB) is more effective than general anesthesia (GA) in elderly individuals undergoing non-cardiac surgeries. The objective of this study was to determine the efficiency of NB in comparison to GA for revascularization of the lower limbs (RLL) in the elderly. ⋯ This metanalysis did not generate enough evidence to demonstrate that NB is more efficient, equivalent, or less efficient than GA for RLL in the elderly.