Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
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Zhong Nan Da Xue Xue Bao Yi Xue Ban · Aug 2011
Randomized Controlled Trial[Protection of noninvasive limb ischemic preconditioning on myocardium in patients undergoing heart valve surgery under cardiopulmonary bypass].
To determine the mechanism of protective effect of noninvasive limb ischemic preconditioning (NIPC) on myocardium of patients with rheumatic heart disease undergoing heart valve surgery under cardiopulmonary bypass (CPB). ⋯ Noninvasive limb ischemic preconditioning can protect the myocardium through increasing CGRP, inhibiting ET-1, and advancing the peak of CGRP and ET-1.
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Zhong Nan Da Xue Xue Bao Yi Xue Ban · Aug 2011
Oridonin induced the apoptosis of PC-3 cells and its mechanism.
To observe the proliferation inhibition and apoptosis promotion effect of oridonin on PC-3 cells. ⋯ The apoptosis of PC-3 cells induced by oridonin might be associated with the mitochondrial pathway.
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Zhong Nan Da Xue Xue Bao Yi Xue Ban · Jul 2011
Incidence and risk factors of intraoperative awareness during general anesthesia.
To investigate the incidence of awareness during general anesthesia and analyze the risk factors in anesthetic practice and patient populations. ⋯ The incidence of intraoperative awareness is high in the clinical practice in major medical centers.
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Zhong Nan Da Xue Xue Bao Yi Xue Ban · Jul 2011
Expression of bone morphogenetic proteins and their receptors in the normal adult rat spinal cord.
To observe the expression distribution of bone morphogenetic proteins (BMP) in the spinal cord of normal adult rats. ⋯ BMP7, BMP receptors, and phosphated pSmad 1/5/8 are expressed in many types of cells whereas BMP2 and BMP4 are not expressed in the spinal cord of normal adult rats, which suggests an important function of BMP signal pathway in the neuron and glia of spinal cord.
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Zhong Nan Da Xue Xue Bao Yi Xue Ban · Jun 2011
Serum concentrations of NSE and S100B in spinocerebellar ataxia type 3/Machado-Joseph disease.
To determine the neuronal damage or loss and gliosis at the cellular level in spinocerebellar ataxia type 3/Machado-Joseph disease(SCA3/MJD), and evaluate the potential use of neuron-specific enolase (NSE) and protein S 100 B(S100B) serum concentrations as biochemical markers. ⋯ Serum NSE might be a useful marker to monitor disease progression and represent the degree of severity of a certain disease. Elevated S100B serum concentrations in patients compared to healthy controls may suggest an application of this protein as a peripheral marker of brain impairment in SCA3/MJD.