Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
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Zhong Nan Da Xue Xue Bao Yi Xue Ban · Feb 2007
[Mechanical valve replacement in children with heart valve diseases].
To determine the surgical point and technique of artificial mechanical valve replacement in children with heart valve diseases. ⋯ The operation mortality was 7.94%(5/63). The follow-up periods were from 4 months to 204 months. The late mortality was 10.34%(6/58). All the other children were in NYHA class I - II. The operation mortality of children with heart valve replacement is higher than that of adults, but it was very effective.
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Zhong Nan Da Xue Xue Bao Yi Xue Ban · Feb 2007
Prospects of using organs and cells from pigs for transplantation into humans.
Once pig organs can be transplanted into humans, transplantation will move into a new era. There will be unlimited access to undamaged organs, and cells for transplantation and, eventually, donation from deceased or live human beings will become obsolete. Furthermore, it will be possible to alleviate graft rejection, at least in part, by genetic modification of the source animal. ⋯ This article will first discuss the ongoing work with regards to overcoming the current obstacles. Also, the many potential advantages of using pig organs will be discussed in some detail. Furthermore, lessons learned from attempts at transplanting porcine cells to patients will be reviewed.
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Zhong Nan Da Xue Xue Bao Yi Xue Ban · Dec 2006
ReviewType 1 diabetes and latent autoimmune diabetes in adults.
The review is aimed to explore the clinical and pathogenic spectrum of autoimmune diabetes including Type 1 diabetes and latent autoimmune diabetes in adults (LADA). Genetic susceptibility modifies age at onset in autoimmune diabetes. The most important genetic susceptibility to Type 1 diabetes and LADA is in the HLA region. ⋯ Non-genetic factors contribute much to Type 1 diabetes, but little is known in LADA. Diabetes-associated immune process can occur in early childhood and can be predictive of an ongoing beta cell destruction. The management and prevention of LADA need to be investigated in order to define the best therapeutic strategy.
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Zhong Nan Da Xue Xue Bao Yi Xue Ban · Dec 2006
Randomized Controlled Trial[Spinal anesthesia with low dose sufentanil-bupivacaine in transurethral resection of the prostate].
To explore the clinical efficacy of intrathecally administered low dose sufentanil-bupivacaine in transurethral resection of the prostate (TURP). METHODS. Ninety patient (ASA I - III) undergoing TURP were randomly divided into 3 groups (n = 30); Group A, B and C. Group A received 7.5 mg bupivacaine + 5 microg sufentanil + 10% glucose; Group B received 7.5 mg bupivacaine + 7.5 microg sufentanil + 10% glucose; Group C received 15 mg bupivacaine + 10% glucose. The volume was 3 mL in every group. SP, DP, HR, SpO2, the degree of motor and sensory blockade and the side effect were observed. ⋯ Spinal anesthesia with low dose sufentanil-bupivacaine possesses relatively steady hemodynamics. The blockade degree of motor and sensory blockade in this spinal anesthesia is lower than that in standard spinal bupivacaine in TURP.
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Zhong Nan Da Xue Xue Bao Yi Xue Ban · Dec 2006
[Continuous veno-venous hemofiltration treatment for acute hypernatremia].
To investigate the effect of continuous veno-venous hemofiltration (CVVHF) for acute hypernatremia. ⋯ CVVHF is effective and can be a new method for treating acute hypernatremia.