Revista médica de Chile
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Revista médica de Chile · Jan 2021
Concordance between estimated glomerular filtration rate using equations and that measured using an imaging method.
Guidelines recommend estimating glomerular filtration rate (GFR) using creatinine-based equations (CBE). ⋯ GFR measured by 99mTc-DTPA radionuclide imaging has a low correlation and poor concordance with estimations using CBE.
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Revista médica de Chile · Jan 2021
[Phospholipase A2 receptor antigen antibodies in serum and renal biopsies of patients with membranous nephropathy].
The discovery of the phospholipase A2 receptor antigen and its highly specific autoantibody (anti-PLA2R Ab) was useful for the diagnosis and follow-up of patients with membranous nephropathy (MN). Thus, some international guidelines recommend not performing renal biopsy in patients with positive serum anti-PLA2R Ab. ⋯ Serum anti-PLA2R Ab is potentially useful in the diagnosis of patients with suspected primary MN in Chilean population.
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A health system is successful when it maintains a healthy population and provides health services that are effective, equitable and safe. ⋯ The design of a multidimensional monitoring system for health access allows us to complement measures usually focused on a specific concept of access (such as utilization, coverage, etc.) with other dimensions. It includes those barriers that are relevant for the Chilean population. It also allows comparisons with other health systems and the generation of evidence to improve public policies.
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Revista médica de Chile · Jan 2021
Randomized Controlled Trial[The impact on sample sizes of studies if the significance level is changed from an α of 0.05 to 0.005].
The statistical significance α = 0.05 is the cut-off point used to decide whether a hypothesis is statistically significant. When p-value is less than 0.05, we reject the null hypothesis. Although this criterion has been used for almost a century to generate new knowledge, there is currently an international discussion about the need to decrease the significance to α = 0.005. ⋯ Considering the sample size implications, the change in the level of significance would have important effects on the Chilean science. The cost of a randomized clinical trial could increase by at least 27% to 32%. This increase could be similar for cross-sectional studies. With an investment of less than 0.4% of gross domestic product in science and technology, national scientific research would become more expensive, distributing the few available resources among fewer projects. This effect should be considered in any discussion about national budget for science and technology.
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Revista médica de Chile · Jan 2021
[Effects of physical exercise on aerobic fitness and cognition in older women with type 2 diabetes mellitus].
Among older people, physical exercise improves cognitive function, aerobic fitness, and thus functional independence. ⋯ A structured walking program improved cognitive function, estimated aerobic capacity, and walking distance in these diabetic women.