Revista médica de Chile
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Revista médica de Chile · Jan 2008
Case Reports[Severe lactic acidosis caused by propofol infusion: report of one case].
Propofol infusion syndrome (PRIS) is a rare but potentially lethal complications. This disorder is triggered under unknown circumstances by a propofol infusion of more than 5 mg/kg/h for more than 48 h. PRIS is characterized by a multiorgan failure and rhabdomyolysis and is induced by a disturbance in mitochondrial long chain fatty acid oxidation. ⋯ In the immediate postoperative period, she had an unexplained and severe lactic acidosis. During anaesthesia, she received a propofol infusion of 7 mg/kg/h that continued in the UCI at a rate of 3.5 mg/kg/h, for 8 hours more. The suspicion of PRIS motivated immediate discontinuation of propofol with rapid correction of lactic acidosis and full recovery of the patient.
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Revista médica de Chile · Oct 2007
Multicenter Study Clinical Trial[Biphasic insulin aspart for the management of diabetic patients with unsatisfactory metabolic control].
Biophasic insulin aspart (InAsBi) is a mixture of 30% of rapid acting soluble aspart insulin and 70% aspart insulin retarded with protamine. The soluble portion reduces postprandial serum glucose rises and the retarded portion reduces basal glucose levels. ⋯ In this group of diabetic patients with a bad metabolic control, the use of InAsBi was associated with a significant reduction of glycosilated hemoglobin levels.
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Revista médica de Chile · Oct 2007
[Intraoperative diastolic dysfunction as a risk factor for hemodynamic instability].
Diastolic function can be evaluated intraoperatively using transesoptiageal echocardiography. ⋯ In this group of patients with cardiovascular disease, intraoperative diastolic dysfunction is a risk factor for hemodynamic instability.
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Revista médica de Chile · Sep 2007
Review[Do antidepressants really increase suicide rates in childhood and adolescence?].
The use of antidepressant in depressive illness results in a reduction of suicidal attempts and deaths due to suicide, conditions that are generally present in this disorder. Recently, the Federal Drug Administration (FDA) prohibited the use of antidepressants during childhood and adolescence. ⋯ It is not possible to ascribe a direct responsibility to antidepressants, because depression, by definition, has suicidal ideation. On the contrary, the reduction of suicidal rates supports the effectiveness of these medications.
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Revista médica de Chile · Aug 2007
[C reactive protein and procalcitonin levels for the diagnosis of invasive bacterial infections in allogenic hematopoietic stem cell transplantation recipients].
The main causes of complications of allogenic hematopoietic stem cell transplantation are infections and graft versus host disease. ⋯ A CRP > or = 90 mg/L or a PCT > or = 0.7 ng/ml had a high specificity and negative predictive value but low sensitivity for the diagnosis of invasive bacterial infections in recipients of allogenic hematopoietic stem cell transplantation.