Revista médica de Chile
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The concept of death has evolved medically, legally and culturally since the introduction of life support technologies in the middle of the 20th century. The traditional cardiopulmonary and the new neurologically based brain death criterions of death are examined. We conclude that brain death, defined as total and irreversible loss of function of the whole brain, fulfills better "the permanent cessation of functioning of the organism as a whole" definition of death. ⋯ Ethics foundations of organ transplantation are reviewed. Even though brain death and organ donation are widely accepted in medical, legal, religious and public opinion today, the whole society and medical community need to be further educated about these matters, so that unavoidable changes of traditional concepts might be better understood. Permanent education should be the best way to dissipate social fears and distrust towards organ donation and brain death.
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This paper undertakes an analysis of the scientific criteria used in the diagnosis of death and underscores the importance of intellectual rigor in the definition of medical concepts, particularly regarding such a critical issue as the diagnosis of death. Under the cardiorespiratory criterion, death is defined as "the irreversible cessation of the functioning of an organism as a whole", and the tests used to confirm this criterion (negative life-signs) are sensitive and specific. In this case, cadaverous phenomena appear immediately following the diagnosis of death. ⋯ It is clear that brain death marks the beginning of a process that eventually ends in death, though death does not occur at that moment. From an ethical point of view, the conflict arises between the need to provide an unequivocal diagnosis of death and the possibility of saving a life through organ transplantation. The sensitive issue of brain death calls for a more thorough and in-depth discussion among physicians and the community at large.
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Delirium or acute confusional state is a condition that lies within the boundaries of psychiatry and other medical specialties. It is defined as a syndrome characterized by a fluctuating cognitive impairment of acute onset. The pathogenesis is multifactorial and it frequently appears in elderly patients admitted to general hospitals. ⋯ This article discusses the most efficient procedures to diagnose and treat delirium. The review was based on a systematic search in the literature using the key words delirium, acute mental syndrome, acute confusional state and organic mental syndrome. Articles were selected according to their relevance and methodological accuracy.
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Revista médica de Chile · Sep 2003
Review[Bioethical aspects of the Health Care Reform in Chile. The problems of access and costs of resources ].
During the process of health reforms there is always the concern that patients rights might be harmed. The bill that is being discussed in the Chilean Parliament contains an special issue dedicated to patient's obligations and rights. However, on the author's opinion, the best protection for patient rights rests on adequate financing and access to a reasonably, good and qualified health care. A thorough revision of the proposals contained in the reform will allow an objective assessment of the eventual ethical problems that it might imply.
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Despite significant advances in the recognition of etiological factors and pathological mechanisms, the pathophysiology of functional gastrointestinal disorders (FGD) is still not fully understood. Visceral hypersensitivity has been recognized as a characteristic of patients with FGD, especially in patients with irritable bowel syndrome (IBS). Visceral afferent input is modulated by a variety of mechanisms, operating between the gastrointestinal tract and the brain. ⋯ Although imaging techniques indicate that there are also differences in cortical activation. Furthermore, selective serotonin reuptake inhibitors may benefit FGD. Recent pharmacological studies suggest that 5-HT3 antagonist such as alosetron and cilansetron, and 5-HT4 agonist such as legaserod and prucalopride may also have a potential use in FGD.