Revista médica de Chile
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Revista médica de Chile · Sep 2024
[Hematopoietic Transplantation Outcomes in Patients with HLA-Identical, Haploidentical, and Unrelated Donors at a University Hospital in Chile].
Allogeneic transplantation (HSCT) is a curative option for several hematological diseases. Our center has privileged the use of identical family donors (IFD) or haploidentical (HD) donors. However, the chances of finding family donors may be challenging in small families or unsuitable donors. In these cases, there is the possibility of obtaining hematopoietic precursors from unrelated donors (URD) with complete or almost complete HLA compatibility. ⋯ our experience shows that the results of DNR, DFI, and DFH are similar. 15% of patients were transplanted with URD because of the absence of suitable family donors.
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Revista médica de Chile · Sep 2024
[Breast Cancer in Male Patients of the Aconcagua Valley During the Period 2013-2018].
Breast cancer in men is a rare disease, accounting for around 1% of all cancers in males. Diagnosis often occurs in advanced stages due to low awareness of this disease in males. ⋯ Despite the limited sample size, the results suggest that factors such as age and clinical and histopathological variables are not significantly associated with survival in men with breast cancer. These findings highlight the need for further research with larger sample sizes to better understand this population's survival factors.
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Revista médica de Chile · Jul 2024
[Tuberculosis Profile in Chile: Effect of Migration, Overcrowding and Income on Tuberculosis and Its Spatial Distribution].
To analyze tuberculosis (TB) incidence, demographic profiles, and associated risk factors in migrant and national populations, in order to understand the impact of migration, overcrowding, and socioeconomic factors on TB prevalence and care-seeking behaviors. ⋯ TB remains a significant public health challenge influenced by migration, overcrowding, and socio-economic disparities. Tailored interventions focusing on high-risk groups and specific geographic areas are essential for effective control strategies. Future research should explore the impact of the COVID-19 pandemic on TB dynamics and associated socio-health factors.
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Revista médica de Chile · Jul 2024
Review Case Reports[Acute Myocardial Infarction as a Presentation of Takayasu Arteritis in a Patient with Ulcerative Colitis: Case Report and Review of the Topic].
A 36-year-old woman with ulcerative colitis presented with progressive chest pain and neurovegetative symptoms. The electrocardiogram showed ST segment elevation in the inferior wall. The patient had a previous history of fatigue and night sweats. ⋯ Aortitis was suspected, which led to additional studies, among which a slight elevation of inflammatory activity indices stood out, and a computed tomography angiography showed periaortic fibrotic thickening and significant stenosis in multiple arteries, suggesting Takayasu vasculitis. She was treated with prednisone and methotrexate and underwent delayed myocardial revascularization surgery with good results. This case highlights the complexity of Takayasu arteritis, its possible association with ulcerative colitis, and the importance of early diagnosis for adequate management.