Revista médica de Chile
-
Revista médica de Chile · Oct 2023
Review[Local advances and challenges in the molecular diagnosis of solid tumors: a health perspective towards precision oncology in Chile].
Cancer will remain one of the most significant challenges for public health, locally and globally. Currently, cancer is the leading cause of death in our country. Thanks to the enormous knowledge accumulated in recent decades on the cellular and molecular bases of cancer, precision oncology has been developed, an approach that allows for increasingly precise pharmacological treatment based on diagnostic tests. ⋯ It is essential to implement these technologies in current and future health systems to optimize the arsenal of strategies for cancer control. This review discusses some of the achievements of precision oncology, particularly applied to solid tumors. It addresses the state-of-the-art minimum biomarkers required for the diagnosis of this important group of neoplasms, the local situation regarding technological capabilities installed in the national territory, either for research or diagnosis, and the potential health impact of applying all this practical knowledge to serve people with cancer, both in the public and private sectors.
-
Revista médica de Chile · Oct 2023
[Benefits and limitations when applying technology to the Integration of prehospital care: a systematic review].
To identify the main benefits and limitations of applying technology in integrating prehospital care into the health network. ⋯ The application of technology in integrating prehospital care into the health network generates benefits and should consider the use of information systems and user satisfaction to achieve integration with health systems, considering the limitations of the context.
-
Revista médica de Chile · Sep 2023
Review[Advances in Nasopharyngeal Carcinoma Treatment: Induction Chemotherapy and Concomitant Radio-Chemotherapy].
Squamous cell carcinoma of the nasopharynx is responsible for 0.7% of all malignant tumors worldwide, with the highest incidence in the population of southern China and Southeast Asia. The standard treatment for locally advanced disease consists of a combination of radiotherapy and chemotherapy in different schedules. Among them, induction chemotherapy followed by concomitant radio-chemotherapy has shown in recent years to be a standard therapeutic option with high rates of locoregional control and overall survival. This paper aims to review the current evidence related to treatment with induction chemotherapy and subsequent radio-chemotherapy in nasopharyngeal cancer, its effectiveness, and the technical aspects of its applicability.
-
Revista médica de Chile · Sep 2023
Review Meta Analysis[Association between Metabolic Syndrome and Risk of Hearing Loss: a Systematic Review and Meta-analysis].
Various studies have linked lifestyle and metabolic diseases to hearing loss. Research on metabolic syndrome has reported a higher prevalence of hearing loss in individuals with it than those without it. ⋯ The findings suggest that both metabolic syndrome and some diseases, such as obesity, diabetes, and hypertension, could be associated with the risk of hearing loss, and control of these diseases could reduce this risk.
-
Revista médica de Chile · Sep 2023
Review Meta Analysis[Association between Metabolic Syndrome and Risk of Hearing Loss: a Systematic Review and Meta-analysis].
Various studies have linked lifestyle and metabolic diseases to hearing loss. Research on metabolic syndrome has reported a higher prevalence of hearing loss in individuals with it than those without it. ⋯ The findings suggest that both metabolic syndrome and some diseases, such as obesity, diabetes, and hypertension, could be associated with the risk of hearing loss, and control of these diseases could reduce this risk.