Revista médica de Chile
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Revista médica de Chile · May 2022
Review[Liver transplantation for non-resectable colorectal liver metastases: A review].
In Chile, colorectal cancer ranks third in incidence and fifth in mortality. Half of these patients have liver metastases at the diagnosis, and only 30% of them are resectable. Despite the development of many complex hepatobiliary procedures to achieve the total resection of metastases, the long-term survival with these techniques is not good. ⋯ These patients have better overall and disease-free survival after liver transplantation. The use of immunosuppressive treatment doesn't increase recurrence, and even the pattern of tumor growth is slower in liver transplant recipients. The purpose of this review is to summarize the current evidence in this topic and to highlight the need for a formal protocol for liver transplantation for unresectable colorectal liver metastases, using living donors or marginal grafts to avoid competition with the rest of the national waiting list.
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Revista médica de Chile · May 2022
Case ReportsUnexpected effect of testosterone in hypergonadotropic hypogonadism and nodular Leydig cell hiperplasia. Report of one case.
We report a 27 -year-old male referred because of hypergonadotropic hypogonadism with low testosterone and azoospermia. At 23 years of age, he underwent an excision of a hypoechoic 0.7 cm nodule of the left testicle. The pathological diagnosis was a Leydig cell tumor. ⋯ With testosterone therapy, LH decreased, and the nodules disappeared. Thereafter, upon interrupting therapy, LH increased, and the nodules reappeared in two occasions. Resuming testosterone treatment, the nodules disappeared again, suggesting a Leydig cell hyperplasia dependent on chronic LH stimulation.
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Revista médica de Chile · May 2022
[Hospital palliative medicine. Revision of a care model implemented at a university hospital].
Palliative Medicine (PM) is a specialty whose objective is to prevent and alleviate suffering associated with advanced diseases. Hospital palliative medicine has benefits in symptom control, quality of life and cost containment. Hospital PM support teams that serve as referral specialists are in charge of a PM care model. ⋯ The hospital PM team proposes a care model that allows the evaluation and a therapeutic approach for patients suffering from advanced diseases, using a multidimensional perspective including their families.
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Revista médica de Chile · May 2022
[Association between early onset of psychoactive drug use and health risk behaviors in chilean adolescents].
Adolescents are more prone to develop health risk behaviors. Among these, early consumption of psychoactive drugs is relevant. ⋯ Early onset of alcohol and illicit drug consumption and smoking is associated with health risk behaviors in Chilean adolescents.
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Acute myeloid leukemia (AML) is the most common leukemia in adults. ⋯ Our results are comparable to those reported in developed countries. Improving the survival of patients 60 years and older is our main challenge.