Mayo Clinic proceedings
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Mayo Clinic proceedings · Aug 2021
Multicenter StudyAcute Pulmonary Embolism During Pregnancy and Puerperium: National Trends and In-Hospital Outcomes.
To investigate the trend and outcomes of acute pulmonary embolism (PE) during pregnancy and puerperium using a large national database. ⋯ In this contemporary analysis of pregnancy-related hospitalizations, acute PE was uncommon, but rates have not decreased over the past decade. Acute PE during pregnancy and puerperium was associated with high maternal mortality, and the rates of in-hospital mortality have not improved. Future studies to improve prevention and management of acute PE during pregnancy and puerperium are warranted.
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Mayo Clinic proceedings · Aug 2021
ReviewA Proposed Approach for Conducting Studies That Use Data From Social Media Platforms.
The prominence of social media in contemporary society has extended significantly into the health care arena, where both patients and health care providers have used social media platforms to gather, communicate, learn, and share medical content and personal experience in real time. The medical literature has also seen an exponential increase in the number of studies that use data derived from social media coverage of various medical issues and topics. ⋯ We present 6 overarching steps: focus on framing a question that is appropriate for social media evaluation, identification of social media outlet and selection criteria of content, systematic data extraction, assessment of quality of content and sources of bias, analysis of data, and interpretation of study findings. Each step is illustrated with published examples.
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Mayo Clinic proceedings · Aug 2021
Multicenter StudyRapid Exclusion of COVID Infection With the Artificial Intelligence Electrocardiogram.
To rapidly exclude severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection using artificial intelligence applied to the electrocardiogram (ECG). ⋯ Infection with SARS-CoV-2 results in electrocardiographic changes that permit the artificial intelligence-enhanced ECG to be used as a rapid screening test with a high negative predictive value (99.2%). This may permit the development of electrocardiography-based tools to rapidly screen individuals for pandemic control.
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Mayo Clinic proceedings · Aug 2021
Readability of Participant Informed Consent Forms and Informational Documents: From Phase 3 COVID-19 Vaccine Clinical Trials in the United States.
To assess the readability of the informed consent forms from the phase 3 COVID-19 vaccine trials conducted in the United States. ⋯ Owing to low readability and several format factors, this study determined that none of the consent forms or informational documents from the recent phase 3 COVID-19 vaccine clinical trials conducted in the United States met readability standards at the recommended 7th grade readability level for the average vaccine research volunteer in any readability category. The average English-speaking vaccine trial volunteer would have great difficulty comprehending the information provided in the consent forms and informational documents. To ensure that study subjects receive and fully comprehend information regarding a clinical study and can provide reliable consent, greater attention should be given to the development and use of simplified consent forms, multimedia formatting, personal discussion, and comprehension assessments.