Mayo Clinic proceedings
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To determine the clinical and laboratory features of newly diagnosed multiple myeloma. ⋯ The median duration of survival was 33 months and did not improve from 1985 through 1998.
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Mayo Clinic proceedings · Jan 2003
Multiple blood donations associated with iron deficiency in patients with restless legs syndrome.
To describe a series of patients with restless legs syndrome (RLS) and iron deficiency with and without anemia related to repeated blood donations. ⋯ Repeated blood donation is associated with induction or perpetuation of RLS due to iron deficiency with or without coexisting anemia. Potential blood donors should be questioned about RLS, and donation should not be allowed until the serum ferritin concentration has been measured and iron stores replenished if necessary.
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Mayo Clinic proceedings · Dec 2002
ReviewAntiepileptic drug therapy for adults: when to initiate and how to choose.
Although antiepileptic drugs (AEDs) are commonly used to control and prevent seizures, their long-term use carries a considerable risk of morbidity. The decision to start AEDs is made once the risks of further seizures outweigh the risks of treatment. ⋯ This article summarizes the current evidence to support individual clinical decisions regarding initiation of AEDs in adults and considers the use of AEDs as seizure prophylaxis. Recently approved AEDs are discussed to help the practitioner understand when to initiate and how to choose the appropriate AED for the patient with seizures.