Mayo Clinic proceedings
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Mayo Clinic proceedings · Jun 2020
Multicenter StudyTime in Therapeutic Range for Dialysis Patients on Warfarin: Determination and the Effect of Dietary Intervention.
This study aimed to identify the time in therapeutic range (TTR) for dialysis patients on warfarin, and improve TTR with dietary review and intervention of interacting foods. We identified 151 patients undergoing hemodialysis in two units who were being treated with warfarin from January 1, 2010, through February 1, 2018, who were included in the overall TTR study. Of these, 15 patients were available to undergo the dietary intervention. ⋯ Among the 15 patients who underwent the intervention, median (IQR) TTR was 52 (IQR, 32 to 56) pre-intervention and 51 (IQR, 38 to 69) post-intervention (P=0.53). TTR for dialysis patients is low in this overall cohort despite patients being seen at an integrated health care system. Focused improvement projects such as dietary review of interacting foods may help increase a patient's TTR.
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Mayo Clinic proceedings · May 2020
Multicenter StudyBrain Volume: An Important Determinant of Functional Outcome After Acute Ischemic Stroke.
To determine whether brain volume is associated with functional outcome after acute ischemic stroke (AIS). ⋯ Larger brain volume quantified on clinical magnetic resonance imaging of patients with AIS at the time of stroke purports a protective mechanism. The role of brain volume as a prognostic, protective biomarker has the potential to forge new areas of research and advance current knowledge of the mechanisms of poststroke recovery.
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Mayo Clinic proceedings · Mar 2020
Multicenter Study Observational StudyPrevalence and Impact of Nonalcoholic Fatty Liver Disease in Atrial Fibrillation.
To estimate the prevalence of nonalcoholic fatty liver disease (NAFLD) and its impact on bleeding and thrombotic events in patients with atrial fibrillation (AF). ⋯ NAFLD is highly prevalent in AF but is not associated with higher bleeding or thrombotic risk.
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Mayo Clinic proceedings · Sep 2019
Multicenter StudyModel for End-Stage Liver Disease Score Predicts Development of First Episode of Spontaneous Bacterial Peritonitis in Patients With Cirrhosis.
To examine whether baseline model for end-stage liver disease (MELD) score in patients with cirrhosis and ascites predicts the future development of first spontaneous bacterial peritonitis (SBP) episode. ⋯ Baseline MELD score predicts first SBP episode in patients with cirrhosis and ascites.
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Mayo Clinic proceedings · Aug 2019
Multicenter Study Comparative StudyComparison of the Short Test of Mental Status and the Montreal Cognitive Assessment Across the Cognitive Spectrum.
To compare the Short Test of Mental Status (STMS) with the Montreal Cognitive Assessment (MoCA) for predicting and detecting mild cognitive impairment (MCI). ⋯ We provide evidence that the STMS performs similarly to the MoCA in a variety of settings and neurodegenerative syndromes. These results suggest that the current recommended MoCA cutoff score may be overly sensitive, consistent with previous studies. We also provide a conversion table for comparing the 2 cognitive tests.