Mayo Clinic proceedings
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Mayo Clinic proceedings · Apr 2024
CoaguChek and Coag-Sense PT2 Meter Point of Care INR Device Validation.
To standardize international normalized ratio (INR) measurements and improve data integrity by enabling electronic result transmission for warfarin monitoring, two point-of-care (POC) devices were evaluated against an internal plasma INR reference method. ⋯ Compared with a plasma referent, INR values obtained from the CoaguChek devices exhibited less systematic bias compared with Coag-Sense measures. This translates to a greater percentage of concordant management decisions between POC and laboratory INR methods.
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Mayo Clinic proceedings · Apr 2024
Blood Calcium, Genetic Risk, and Risk of Incident Kidney Stone: A Population-Based Cohort Study.
To investigate the association between blood calcium concentration and incident kidney stone as well as to assess the role played by genetic susceptibility. ⋯ Blood calcium concentration and PRS are significantly associated with incident kidney stone risk. Excessive blood calcium concentration might bring additional stone risk in populations at high genetic risk. A nonlinear correlation between blood calcium concentration and kidney stone risk was indicated.
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Mayo Clinic proceedings · Apr 2024
Incident Diuretic Use and Subsequent Risk of Bone Fractures: A Large Nationwide Observational Study of US Veterans.
To investigate the association of incident use of diuretics with subsequent risk of incident bone fractures. ⋯ Incident use of diuretics, particularly loop diuretics, was independently associated with higher risk of incident bone fractures. Our findings suggest distinct pathophysiologic contributions of diuretics to bone metabolism and the need for careful attention to skeletal outcomes when initiating diuretics.
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Mayo Clinic proceedings · Apr 2024
Predicting Primary Care Physician Burnout From Electronic Health Record Use Measures.
To evaluate the ability of routinely collected electronic health record (EHR) use measures to predict clinical work units at increased risk of burnout and potentially most in need of targeted interventions. ⋯ In a sample of primary care physicians, routinely collected EHR use measures demonstrated limited ability to predict individual burnout and moderate ability to identify high-risk clinics.