Minerva stomatologica
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Minerva stomatologica · Jul 2011
Randomized Controlled Trial Comparative StudyComparison by means of bispectral index score, between anxiolysis induced by diazepam and sedation induced by midazolam.
Bispectral Index Score (BIS) is an objective tool to assess sedation depth. Benzodiazepines have different pharmacological profiles and diazepam may be safer than midazolam in this setting. The aim of this study was to compare BIS values observed during anxiolysis after diazepam versus sedation after midazolam. ⋯ Diazepam has a safer profile, with BIS values and clinical conditions according to the definition of minimal and/or moderate sedation. Diazepam represents the safer drug for anxiety management in dentistry, because regularly produces a state of sedation during which verbal contact with the patient is maintained and carry a margin of safety wide enough to render loss of consciousness unlikely.
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Minerva stomatologica · Sep 2010
Randomized Controlled Trial Comparative StudyPatients appreciation for information on anesthesia and anxiolysis in dentistry.
The research regards information on anesthesia to patients undergoing oral surgery. Every patient evaluated the information received at the end of the preoperative visit and in the postoperative period. ⋯ The information on the anxiolytic techniques, loco-regional anesthesia, treatment of perioperative pain and postoperative distress was enthusiastically accepted and albeit initially induced feelings of astonishment resulted to be appreciated and preferred in the whole of the patients.
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Minerva stomatologica · Mar 2007
Randomized Controlled TrialBispectral Index in the sedation with intranasal midazolam and intravenous diazepam in dental practice.
Aim of this study was to assess by clinical evaluation and by Bispectral Index (BIS) the tranquillizing properties of diazepam injected intravenously, and midazolam by intranasal route according to the body weight in dental patients. ⋯ The study shows that nasal route ensures the quick absorption of midazolam as revealed during the first 3 min from drug administration. The depressant effect of midazolam increased as a function of time, reaching the highest levels during intervention. The results suggest that midazolam is endowed with sedative effects which may compromise the state of consciousness of the patient and be incompatible with the definition of conscious sedation in dentistry.
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Minerva stomatologica · Mar 2006
Randomized Controlled Trial Comparative StudyNeurosedation in dentistry of the disabled patient: the use of midazolam, propofol, and remifentanil.
This prospective randomized study, deals with neurosedation in dental treatment of 200 disabled patients and unable to cooperate, subdivided in 4 groups of 50 male only patients, with age ranging from 28 to 59 (39+/-11), ASA I-III. ⋯ This combination proved best at leveraging the synergistic characteristics of each single pharmaceutical and minimizing the collateral effects of each individually.
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Minerva stomatologica · Sep 2002
Randomized Controlled Trial Comparative Study Clinical TrialBurning mouth syndrome (BMS): an open trial of comparative efficacy of alpha-lipoic acid (thioctic acid) with other therapies.
Alpha-lipoic acid (ALA) is a potent antioxidant mitochondrial coenzyme, trometamol salt of thioctic acid, shown in clinical studies to be neuroprotective and in a preliminary study to have an effect on the symptomatology of Burning Mouth Syndrome (BMS). ⋯ These results suggest that double-blind randomized controlled multicenter studies of ALA are indicated.