Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology
The most recent articles from:
March 2014
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Zhongguo Ying Yong Sheng Li Xue Za Zhi · Mar 2014
[The protective role of interleukin-6 monoclonal antibody on experimental autoimmune myocarditis and its mechanism].
To investigate the therapeutic effect of IL-6 mAb on experimental autoimmune myocarditis (EAM) in rats, and search the mechanism of the role of IL-6, helper T cells 17 (Th17) and regulative T cells (Treg) in EAM pathogenesis. ⋯ IL-6 mAb could neutralize IL-6, and ameliorate myocarditis and reduce heart autoimmune responses. IL-6 mAb has significantly protective effects on EAM by suppressing Th17 and Treg cells.