Diabetes/metabolism research and reviews
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Diabetes Metab. Res. Rev. · Oct 2015
Trends in the incidence of diabetes, its clinical sequelae, and associated costs in pregnancy.
Increasing diabetes prevalence affects a substantial number of pregnant women in the United States. Our aims were to evaluate health outcomes, medical costs, risks and types of complications associated with diabetes in pregnancy for mothers and newborns. ⋯ Complications and costs of healthcare were greater with diabetes, highlighting the need to optimize diabetes management in pregnancy.
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Diabetes Metab. Res. Rev. · Oct 2015
The changes in miR-130b levels in human serum and the correlation with the severity of diabetic nephropathy.
Circulating microRNA 130b has been closely associated with multiple diseases in humans such as cancer, obesity and diabetes mellitus. This study evaluates the correlation between serum miR-130b and the severity of diabetic nephropathy evaluated by measurement of albuminuria. ⋯ Our findings suggest that serum miR-130b may be a new biomarker for the early diagnosis of DN in T2DM. Circulating miR-130b may possibly be involved in the pathological mechanism of DN, such as lipid metabolic disorders, oxidative stress, extracellular matrix deposition and renal fibrosis.