BJOG : an international journal of obstetrics and gynaecology
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Randomized Controlled Trial Multicenter Study
Recurrence of vulval intraepithelial neoplasia following treatment with cidofovir or imiquimod: results from a multicentre, randomised, phase II trial (RT3VIN).
To compare the recurrence rates after complete response to topical treatment with either cidofovir or imiquimod for vulval intraepithelial neoplasia (VIN) 3. ⋯ Long-term data indicates a trend towards response being maintained for longer following treatment with cidofovir than with imiquimod, with similar low rates of adverse events for each drug. Adverse event rates indicated acceptable safety of both drugs TWEETABLE ABSTRACT: Long-term follow up in the RT3VIN trial suggests cidofovir may maintain response for longer than imiquimod.
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To examine hospital variation in cost of childbirth hospitalisations and identify factors that contribute to the variation. ⋯ Hospitals vary in cost of childbirth. Institutional characteristics significantly contribute to the variation.
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Comparative Study
Perinatal and maternal morbidity and mortality among term singletons following midcavity operative vaginal delivery versus caesarean delivery.
To quantify severe perinatal and maternal morbidity/mortality associated with midcavity operative vaginal delivery compared with caesarean delivery. ⋯ Perinatal and maternal morbidity is increased following midcavity operative vaginal delivery.