BJOG : an international journal of obstetrics and gynaecology
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Randomized Controlled Trial Multicenter Study
World Health Organisation multicentre randomised trial of supplementation with vitamins C and E among pregnant women at high risk for pre-eclampsia in populations of low nutritional status from developing countries.
To determine if vitamin C and E supplementation in high-risk pregnant women with low nutritional status reduces pre-eclampsia. ⋯ Vitamins C and E at the doses used did not prevent pre-eclampsia in these high-risk women.
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Randomized Controlled Trial
Iron supplement in pregnancy and development of gestational diabetes--a randomised placebo-controlled trial.
To test the hypothesis that iron supplement from early pregnancy would increase the risk of gestational diabetes mellitus (GDM). ⋯ Iron supplement from early pregnancy does not increase the risk of GDM. It may have benefits in terms of pregnancy outcomes.
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Randomized Controlled Trial Multicenter Study
Early versus delayed oxytocin augmentation in nulliparous women with prolonged labour--a randomised controlled trial.
To study the effects of early versus delayed oxytocin augmentation on the obstetrical and neonatal outcome in nulliparous women with spontaneous but prolonged labour. ⋯ Early administration of oxytocin did not change the rate of caesarean section or instrumental vaginal delivery but shortened labour duration significantly in women with a 2-hour arrest in cervical dilatation. No other clear benefits or harms were seen between early and delayed administration of oxytocin.
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Randomized Controlled Trial
Ear acupuncture or local anaesthetics as pain relief during postpartum surgical repair: a randomised controlled trial.
To evaluate two methods of pain relief during postpartum surgical repair in regard to effectiveness, wound healing and patient evaluation. ⋯ Ear acupuncture as used in this trial was less effective for pain relief compared with a local anaesthetic. No difference was observed in wound healing, need for revision of wound or dyspareunia. Patient satisfaction with allocated pain-relief method was lower in the ear acupuncture group.
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Randomized Controlled Trial Multicenter Study
Titrated low-dose vaginal and/or oral misoprostol to induce labour for prelabour membrane rupture: a randomised trial.
To evaluate the clinical effectiveness and safety of titrated low-dose misoprostol for induction of labour (IOL) in the presence of prelabour rupture of membranes (PROM). ⋯ Titrated low-dose misoprostol may be a reasonable alternative for IOL in the presence of PROM, particularly in women with an unfavourable cervix. Safety and rare serious adverse events could not be evaluated in a trial of this size.