BJOG : an international journal of obstetrics and gynaecology
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Randomized Controlled Trial Comparative Study
Comparison of self-administered vaginal misoprostol versus placebo for cervical ripening prior to operative hysteroscopy using a sequential trial design.
To compare the impact of 1000 micrograms of self-administered vaginal misoprostol versus self-administered vaginal placebo at home on preoperative cervical ripening in both premenopausal and postmenopausal women before operative hysteroscopy. ⋯ One thousand micrograms of self-administered vaginal misoprostol 12 hours prior to operative hysteroscopy has a significant cervical ripening effect compared with placebo in premenopausal but not in postmenopausal women. Self-administered vaginal misoprostol of 1000 micrograms at home the evening before operative hysteroscopy is safe and highly acceptable, although a small proportion of women experienced severe lower abdominal pain. There is a risk of lower abdominal pain and light preoperative bleeding with this regimen, which is very cheap and easy to use.
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Randomized Controlled Trial Multicenter Study
Use of a decision aid for prenatal testing of fetal abnormalities to improve women's informed decision making: a cluster randomised controlled trial [ISRCTN22532458].
To evaluate the effectiveness of a decision aid for prenatal testing of fetal abnormalities compared with a pamphlet in supporting women's decision making. ⋯ A tailored prenatal testing decision aid plays an important role in improving women's knowledge of first and second trimester screening tests and assisting them to make decisions about screening and diagnostic tests that are consistent with their values.
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Randomized Controlled Trial
The effect of early versus delayed postcaesarean feeding on women's satisfaction: a randomised controlled trial.
To evaluate the effect of early versus delayed feeding after caesarean section on the woman's satisfaction. ⋯ Early feeding after uncomplicated caesarean in low-risk women is equivalent in terms of the woman's satisfaction and the reduced perceived pain.
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Randomized Controlled Trial Comparative Study
Five-year follow up of a randomised controlled trial comparing NovaSure and ThermaChoice endometrial ablation.
We have previously reported that NovaSure was more effective than balloon ablation at 12 months follow up in the treatment of menorrhagia. In this paper, we report the 5-year outcome of this study. The objective was to evaluate amenorrhoea rates, hysterectomy rate, and quality of life associated with the bipolar impedance-controlled endometrial ablation technique (NovaSure) in comparison with balloon ablation technique (ThermaChoice) at 5 years after administration. ⋯ At 5 years follow up, bipolar thermal ablation was superior over balloon ablation in the treatment of menorrhagia.
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Randomized Controlled Trial
A randomised controlled trial of prophylactic levonorgestrel intrauterine system in tamoxifen-treated women.
To study the prophylactic use of levonorgestrel intrauterine system (LNG-IUS) in the prevention of endometrial pathology in women having breast cancer treated with tamoxifen. ⋯ LNG-IUS reduces the occurrence of de novo endometrial polyp in women treated with tamoxifen for breast cancer.