BJOG : an international journal of obstetrics and gynaecology
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Randomized Controlled Trial Multicenter Study
An economic evaluation of tranexamic acid to prevent postpartum haemorrhage in women with vaginal delivery: the randomised controlled TRAAP trial.
To estimate the cost-effectiveness of tranexamic acid (TXA) use to prevent postpartum haemorrhage. ⋯ Tranexamic acid at vaginal delivery reduces both costs and bleeding events 3 times out of 4.
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Randomized Controlled Trial
Virtual reality for acute pain in outpatient hysteroscopy: a randomised controlled trial.
To evaluate the effectiveness of virtual reality as a distraction technique in the management of acute pain and anxiety during outpatient hysteroscopy. ⋯ Virtual reality can be used as a part of a multimodal strategy to reduce acute pain and anxiety in patients undergoing outpatient hysteroscopy.
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Randomized Controlled Trial Comparative Study
Carbetocin versus oxytocin for the prevention of postpartum haemorrhage following caesarean section: the results of a double-blind randomised trial.
To compare the effectiveness of carbetocin and oxytocin when they are administered after caesarean section for prevention of postpartum haemorrhage (PPH). ⋯ Carbetocin is associated with a reduced use of additional oxytocics. It is unclear whether this may reduce rates of PPH and blood transfusions.
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To estimate prevalence of vaping in pregnancy. Compare characteristics and attitudes between exclusive smokers and vapers, and between exclusive vapers and dual users (smoke and vape). ⋯ One in 20 women report vaping during pregnancy but of those that do vape, most also smoke, despite having intentions to quit.
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Randomized Controlled Trial Comparative Study
Haemodynamic effects of carbetocin and oxytocin given as intravenous bolus on women undergoing caesarean delivery: a randomised trial.
This study compares the maternal heart rate effects of carbetocin and oxytocin during elective caesarean delivery. ⋯ Both oxytocins have comparable haemodynamic effects and are uterotonic drugs with an acceptable safety profile for prophylactic use. Minimal differences in the recovery phase beyond 70 seconds are in keeping with the fact that carbetocin has an extended half-life compared with oxytocin.