BJOG : an international journal of obstetrics and gynaecology
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To develop a set of core outcomes for studies on pregnant women with epilepsy. ⋯ A Delphi method identifying core outcomes for epilepsy in pregnancy. Final core set includes 31 outcomes.
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Observational Study
Small lesion size measured by colposcopy may predict absence of cervical intraepithelial neoplasia in a large loop excision of the transformation zone specimen.
To evaluate whether colposcopic measurement of the lesion size at diagnosis and/or human papillomavirus (HPV) genotyping can predict the absence of dysplasia in a large loop excision of the transformation zone (LLETZ) specimen in women treated for squamous intraepithelial lesions/cervical intraepithelial neoplasia (SIL/CIN). ⋯ Small lesion size in colposcopic evaluation might predict the absence of SIL/CIN in an LLETZ specimen.
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Review Meta Analysis
Surgical lymph node assessment in mucinous ovarian carcinoma staging: a systematic review and meta-analysis.
The proportion of women with mucinous ovarian carcinoma in whom nodal metastases are identified during staging remains unclear. ⋯ Surgical lymph node assessment in women with stage I-II mucinous ovarian cancer rarely has staging consequences.
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Localised provoked vulvodynia (LPV) is a common, chronic, and disabling condition: patients experience profound pain and a diminished quality of life. The aetiologic origins of vulvodynia are poorly understood, yet recent evidence suggests a link to site-specific inflammatory responses. ⋯ Although LPV is a multifactorial disorder, understanding vulvar inflammation and targeting the inflammatory response should lead to treatment advances, especially for patients exhibiting signs of inflammation. NFκB (already targeted clinically) or other inflammatory components may be suitable therapeutic targets.