BJOG : an international journal of obstetrics and gynaecology
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Randomized Controlled Trial Clinical Trial
Anxiety levels in women attending colposcopy clinics for treatment for cervical intraepithelial neoplasia: a randomised trial of written and video information.
To assess the effectiveness of video information in reducing the level of anxiety in women attending Colposcopy clinics. ⋯ Women attending colposcopy clinics for either diagnosis or treatment, experience a high level of anxiety. The highest levels occur in women attending a one-stop see and treat clinic. The introduction of visual information in the form of an explanatory video prior to attendance significantly reduced anxiety.
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Randomized Controlled Trial Multicenter Study Clinical Trial
Women's views on the practice of prenatal perineal massage.
To determine how women who practised perineal massage during pregnancy assessed the technique. ⋯ Overall, women's assessment of prenatal perineal massage is positive.
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Randomized Controlled Trial Comparative Study Clinical Trial
A comparison of isosorbide mononitrate, misoprostol and combination therapy for first trimester pre-operative cervical ripening: a randomised controlled trial.
To determine whether a combined therapy with isosorbide mononitrate (40mg) and misoprostol (400 microg) for pre-operative cervical ripening in the first trimester would result in improved clinical effectiveness, and fewer side effects compared with each agent used alone. ⋯ We have not shown any advantage of combining misoprostol with the nitric oxide donor isosorbide mononitrate compared with misoprostol alone for pre-operative cervical ripening in the first trimester.
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Effectiveness and safety of the oxytocin antagonist atosiban versus beta-adrenergic agonists in the treatment of preterm labour. The Worldwide Atosiban versus Beta-agonists Study Group.
To compare the effectiveness and safety of the oxytocin antagonist atosiban with conventional beta-adrenergic agonist (beta-agonist) therapy in the treatment of preterm labour. ⋯ In the largest study of tocolytic therapy to date, atosiban was comparable in clinical effectiveness to conventional beta-agonist therapy, but was associated with fewer maternal cardiovascular side effects. We conclude that atosiban has clinical advantages over current tocolytic therapy.
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Randomized Controlled Trial Clinical Trial
A randomised controlled trial of antibiotic prophylaxis in elective caesarean delivery.
To determine whether prophylactic antibiotic administration using cefoxitin at the time of elective caesarean section significantly reduces infectious morbidity. ⋯ Antibiotic prophylaxis with cefoxitin in elective caesarean section did not reduce post-operative infectious morbidity in this double-blind randomised placebo controlled trial.