The lancet oncology
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The lancet oncology · Sep 2014
Review Meta AnalysisTrilateral retinoblastoma: a systematic review and meta-analysis.
About 5% of children with retinoblastoma from germline mutation of the RB1 gene are at risk of developing trilateral retinoblastoma--intraocular retinoblastoma combined with a histologically similar brain tumour, most commonly in the pineal gland. We aimed to provide a systematic overview of published data for trilateral retinoblastoma, and to analyse how survival has changed. ⋯ None.