Emergency medicine journal : EMJ
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Review Meta Analysis
Oxygen therapy for acute myocardial infarction: a systematic review and meta-analysis.
Oxygen (O(2)) is widely recommended in international guidelines for treatment of acute myocardial infarction (AMI), but there is uncertainty about its safety and benefits. A systematic review and meta-analysis were performed to determine whether inhaled O(2) in AMI improves pain or the risk of death. Cochrane CENTRAL Register of Controlled Trials, MEDLINE, MEDLINE In-Process, EMBASE, CINAHL, LILACS and PASCAL were searched from start date to February 2010. ⋯ Evidence for O(2) in AMI is sparse, of poor quality and pre-dates advances in reperfusion and trial methods. Evidence is suggestive of harm but lacks power and excess deaths in the O(2) group could be due to chance. More research is required.
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Review Meta Analysis
Meta-analysis of controlled studies on immunotherapy in severe scorpion envenomation.
Despite conflicting evidence, specific serotherapy is recommended for scorpion envenomation. ⋯ SAV should not be administered in Old World scorpion envenomation until its efficacy is established by an appropriately designed RCT. In the Arizona scorpion sting, SAV hastens the recovery process.