Emergency medicine journal : EMJ
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A short cut review was performed to seek the evidence for use of intravenous lipid emulsion in the treatment of overdose with β-receptor antagonists. Eight case reports and one case series with a total of 10 patients were found. The authors, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses are tabulated. The clinical bottom line is that there is only anecdotal evidence of effectiveness for this treatment.
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A short cut review was performed to assess the utility of a skeletal survey in patients with suspected non-accidental injury. Three studies including a total of 983 patients were found. The authors, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses are tabulated. The clinical bottom line is that skeletal surveys are useful in children who are suspected to have non-accidental injury, particularly in those aged under 1 year.
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Review Meta Analysis
Oxygen therapy for acute myocardial infarction: a systematic review and meta-analysis.
Oxygen (O(2)) is widely recommended in international guidelines for treatment of acute myocardial infarction (AMI), but there is uncertainty about its safety and benefits. A systematic review and meta-analysis were performed to determine whether inhaled O(2) in AMI improves pain or the risk of death. Cochrane CENTRAL Register of Controlled Trials, MEDLINE, MEDLINE In-Process, EMBASE, CINAHL, LILACS and PASCAL were searched from start date to February 2010. ⋯ Evidence for O(2) in AMI is sparse, of poor quality and pre-dates advances in reperfusion and trial methods. Evidence is suggestive of harm but lacks power and excess deaths in the O(2) group could be due to chance. More research is required.
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Review Meta Analysis
Meta-analysis of controlled studies on immunotherapy in severe scorpion envenomation.
Despite conflicting evidence, specific serotherapy is recommended for scorpion envenomation. ⋯ SAV should not be administered in Old World scorpion envenomation until its efficacy is established by an appropriately designed RCT. In the Arizona scorpion sting, SAV hastens the recovery process.
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A short cut review was performed to assess the effect of the presence of family members on the efficiency of paediatric trauma resuscitation. Two studies with a total of 999 patients were included. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses are tabulated. The clinical bottom line is that the presence of the patient's family does not adversely affect the outcome of paediatric trauma resuscitation.