Arquivos de neuro-psiquiatria
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Randomized Controlled Trial
Liposomal topical capsaicin in post-herpetic neuralgia: a safety pilot study.
Topical treatments have gained popularity for general use as an adjunct to systemic drugs in neuropathic pain, but their use produces variable clinical results and local adverse events. ⋯ Thirteen patients completed both treatment periods. Visual Analog Scale (VAS) was significantly decreased after the end of the study (p = 0.008), however the effect of treatment was not significant (p = 0.076). There was no difference on global impression of change and other pain characteristics. LC was safe and well tolerated. However, at the concentration used, its analgesic effects were marginal and not significant.
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Randomized Controlled Trial
Amitriptyline and aerobic exercise or amitriptyline alone in the treatment of chronic migraine: a randomized comparative study.
To compare the preventive treatment benefits of amitriptyline and aerobic exercise or amitriptyline alone in patients with chronic migraine. ⋯ In this study, the amitriptyline was an effective treatment for chronic migraine, but its efficacy was increased when combined with aerobic exercise.
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Randomized Controlled Trial
Effects of botulinum toxin type A for spastic foot in post-stroke patients enrolled in a rehabilitation program.
The objective of this study was to evaluate the effects of botulinum toxin type A (BTX-A) on spastic foot in stroke patients in a rehabilitation program. ⋯ Our findings suggest that gains in gait velocity and functional independence were not correlated to BTX-A dose.
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Randomized Controlled Trial
The cognitive behavioral therapy causes an improvement in quality of life in patients with chronic musculoskeletal pain.
Chronic pain causes functional incapacity and compromises an individual's affective, social, and economic life. ⋯ The CBT was effective and it has caused an improvement in more domains of quality of life when compared to the Control Group, after ten weeks of treatment.
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Randomized Controlled Trial Comparative Study
Intensive insulin therapy versus conventional glycemic control in patients with acute neurological injury: a prospective controlled trial.
To compare intensive insulin therapy to conventional glycemic control in patients with acute neurological injury evaluating neurological outcome and morbimortality. ⋯ A less strict intensive insulin therapy can reduce hypoglycemia and still maintain its benefits.