Revista de actualidad estomatológica española / Ilustre Consejo General de Colegios de Odontólogos y Estomatólogos de España
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Rev Actual Estomatol Esp
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A brief historical review of man's attempts to produce pain relief is presented, from physical measures: compression, application of cold, to anesthetic gases and up to the introduction of cocaine and its synthetic derivatives. These offer us now a wide range of drugs with characteristics and properties of local anesthetics which are more and more effective and at the same time with fewer undesirable side effects.