Articles: trauma.
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Pediatric emergency care · Jul 2014
Cumulative Effective Dose Associated With Computed Tomography Examinations in Adolescent Trauma Patients.
The aims of this study were to analyze cumulative effective dose (cED) and to assess lifetime attributable risk (LAR) of cancer due to radiation exposure during computed tomography (CT) examinations in adolescent trauma patients. ⋯ The overall radiation-induced cancer risk due to CT examinations performed for the initial assessment of minor trauma was found to be relatively low in adolescent patients. However, adolescent patients with major trauma were exposed to a substantial amount of radiation during multiple CT examinations.
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Seminars in ophthalmology · Jul 2014
Reliability of ocular ultrasonography findings for pre-surgical evaluation in various vitreo-retinal disorders.
To find the reliability of ocular ultrasonography (USG) for pre-surgical evaluation in various vitreo-retinal conditions. ⋯ Our study highlighted that the reliability of USG findings was least in cases of trauma, hence requiring special care while reporting.
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Cardiac tamponade (CT) is a clinical entity characterized by hemodynamic insufficiency resulting from increased intrapericardial pressure due to accumulation of contents such as serous fluid, blood, and pus. CT is a treatable cause of cardiogenic shock, which can be fatal unless diagnosed promptly. ⋯ Idiopathic or viral pericardititis, iatrogenic trauma during percutaneous coronary interventions or coronary artery bypass grafting, external trauma, malignancies, acute or chronic kidney disease, collagen vascular diseases, tuberculosis, radiation on the chest wall, hypothyroidism and aortic dissection are the etiologic factors. Herein, we present a case of surgically treated CT, which was diagnosed in the third day of ingestion of a sewing needle.
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Journal of neurotrauma · Jul 2014
Delayed Increases in Microvascular Pathology Following Experimental Traumatic Brain Injury Are Associated with Prolonged Inflammation, Blood Brain Barrier Disruption and Progressive White Matter Damage.
Traumatic brain injury (TBI) is a significant risk factor for chronic traumatic encephalopathy (CTE), Alzheimer's disease (AD), and Parkinson's disease (PD). Cerebral microbleeds, focal inflammation, and white matter damage are associated with many neurological and neurodegenerative disorders including CTE, AD, PD, vascular dementia, stroke, and TBI. This study evaluates microvascular abnormalities observed at acute and chronic stages following TBI in rats, and examines pathological processes associated with these abnormalities. ⋯ Microbleeds were surrounded by glial scars and co-localized with CD68 and IgG puncta stainings, suggesting that localized BBB breakdown and inflammation were associated with vascular damage. Our results indicate that evolving white matter degeneration following experimental TBI is associated with significantly delayed microvascular damage and focal microbleeds that are temporally and regionally associated with development of punctate BBB breakdown and progressive inflammatory responses. Increased understanding of mechanisms underlying delayed microvascular damage following TBI could provide novel insights into chronic pathological responses to TBI and potential common mechanisms underlying TBI and neurodegenerative diseases.
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The purpose of this study was to evaluate community member feedback from community consultation and public disclosure activities performed for a clinical investigation involving a device designed to treat traumatic brain injury in prehospital contexts. The clinical investigation of that device was to be performed under the federal regulations providing an exception from prospective informed consent requirements in emergency settings. Secondarily, we sought to assess the community consultation process by measuring the levels of outreach provided by the different communication methods used in these activities, with special attention to the effectiveness of social media for community outreach. ⋯ The internal and external websites provided the most effective means for sharing research-related information to community members. While cost-effective, social media outreach was very limited and did not foster communication with community members.