Articles: trauma.
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Intestinal ischemia and reperfusion (intestinal I/R) causes acute lung inflammation that is characterized by leukocyte migration, increased lung microvascular permeability, and, in severe forms, noncardiogenic pulmonary edema and acute respiratory distress syndrome. Female sex hormones interfere with immune response, and experimental and clinical evidence shows that females are more resistant than males to organ injury caused by gut trauma. To reduce the lung inflammation caused by intestinal I/R, we have acutely treated male rats with estradiol. ⋯ The treatment with E2 did not affect NOx concentration. Taken together, our data suggest that estradiol modulates the lung inflammatory response induced by lung injury, likely by acute effects. Thus, acute estradiol treatment could be considered as a potential therapeutic agent in ischemic events.
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Pleural Case Report PostersSESSION TYPE: Case Report PosterPRESENTED ON: Sunday, March 23, 2014 at 01:15 PM - 02:15 PMINTRODUCTION: Thoracic splenosis should be suspected in a patient with pulmonary nodules and history of splenic trauma. ⋯ In conclusion, thoracic splenosis is considered a benign process, and should be suspected in a patient with any CT or MRI demonstrating left pulmonary nodules with history of splenic trauma. Though new non invasive studies are available and are preferred to the invasive studies, the CT guided biopsy was done to rule out malignancy found on the initial chest CT.Reference #1: Malik U (2010). Parenchymal Thoracic Splenosis: history and nuclear imaging without invasive procedures may provide diagnosis. J Clin Med Res. 2(4),180-184.Reference #2: Mancano A (2012). Thoracic splenosis after thoracoabdominal trauma presenting as pleural nodules. Lung. 190(6), 699-701.Reference #3: Sahin E. (2009). Thoracic splenosis accompanied by diaphragmatic hernia. Can J Surg. 52, E293-294DISCLOSURE: The following authors have nothing to disclose: Ashraf Elsawaf, Jonathan Banibensu, Heather BoakyeNo Product/Research Disclosure Information.
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Cardiovascular CasesSESSION TYPE: Case ReportsPRESENTED ON: Saturday, March 22, 2014 at 04:15 PM - 05:15 PMINTRODUCTION: Paroxysmal supraventricular tachycardia (PSVT) following blunt cardiac injury (BCI) is rare but reported in the literature. AV nodal reentrant tachycardia (AVNRT) is the commonest form of PSVT encountered in clinical practice. We present a unique case of AVNRT after a blunt chest trauma with concomitant pulmonary embolism. ⋯ This case illustrates two unusual sequelae of blunt chest trauma-- pulmonary embolus and sustained AV nodal reentrant tachycardia.Reference #1: "Trauma Associated With Cardiac Dysrhythmias: Results Froma Large Matched Case-Control Study." Ismailov et al. The Journal of Trauma Injury, Infection, and Critical Care. 2007;62.Reference #2: "Blunt cardiac injury." Bock et al. Cardiology Clinics. Volume 30, Issue 4, November 2012.Reference #3: "Thromboembolism as a complication of myocardial contusion: a new capricious syndrome." Timberlake et al. Journal of Trauma. 1988 April 28(4)DISCLOSURE: The following authors have nothing to disclose: Joy Victor, Mangalore Amith Shenoy, Sameer Chadha, Felix Yang, Gerald Hollander, Jacob ShaniNo Product/Research Disclosure Information.
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Cardiovascular Case Report Posters ISESSION TYPE: Case Report PosterPRESENTED ON: Sunday, March 23, 2014 at 01:15 PM - 02:15 PMINTRODUCTION: Central venous catheters (CVC) are placed in large caliber veins, and though relatively safe, complications can occur. When chest radiograph cannot verify proper CVC placement, further assessments are mandated. We present a case of questionable placement of a left-sided CVC. ⋯ The following authors have nothing to disclose: Andrew Oh, Andrew SchaffrinnaNo Product/Research Disclosure Information.
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Determining the appropriate disposition of emergency department (ED) syncope patients is challenging. Previously developed decision tools have poor diagnostic test characteristics and methodological flaws in their derivation that preclude their use. We sought to develop a scale to risk-stratify adult ED syncope patients at risk for serious adverse events (SAEs) within 30 days. ⋯ We derived a risk scale that accurately predicts SAEs within 30 days in ED syncope patients. If validated, this will be a potentially useful clinical decision tool for emergency physicians, may allow judicious use of health care resources, and may improve patient care and safety.