Articles: out-of-hospital-cardiac-arrest.
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Review Retracted Publication
Epinephrine for out of hospital cardiac arrest: A systematic review and meta-analysis of randomized controlled trials.
To evaluate the effectiveness of epinephrine, compared with control treatments, on survival at admission, ROSC, survival at discharge, and a favorable neurologic outcome in adult patients during OHCA. ⋯ In OHCA, standard or high doses of epinephrine should be used because they improved survival to hospital discharge and resulted in a meaningful clinical outcome. There was also a clear advantage of using epinephrine over a placebo or no drugs in the considered outcomes.
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Retraction Of Publication Multicenter Study Observational Study
Inflammatory Markers Following Resuscitation from Out-of-Hospital Cardiac Arrest - a Prospective Multicenter Observational Study.
The post-cardiac arrest syndrome is a complex set of pathophysiological processes including a systemic inflammatory response. The goal of the current investigation was to test the hypothesis that early inflammatory markers are independently associated with in-hospital mortality and poor neurological outcome in patients initially resuscitated from out-of-hospital cardiac arrest. ⋯ Early inflammatory markers, especially IL-6, are higher in patients with a poor outcome after OHCA. IL-6 remained associated with mortality, but not functional outcome, in multivariable analysis adjusting for patient and event characteristics.