Articles: middle-aged.
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J. Neurol. Neurosurg. Psychiatr. · Dec 2016
Metabolic syndrome is related to polyneuropathy and impaired peripheral nerve function: a prospective population-based cohort study.
Diabetes mellitus is a known risk factor for polyneuropathy, but the role of pre-diabetes and metabolic syndrome remains unclear. We aimed to investigate the role of these factors in a community-dwelling middle-aged and elderly population. ⋯ Metabolic syndrome, abdominal obesity and dyslipidaemia, are strongly associated with polyneuropathy, irrespective of the presence of diabetes. Metabolic syndrome also associates with impaired nerve function in people without polyneuropathy. Our study therefore suggests that cardiometabolic disturbances have an impact on peripheral nerve function that extends beyond clinically manifest disease.
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The neural underpinnings of impaired consciousness and of the variable severity of behavioural deficits from one absence seizure to the next are not well understood. We aimed to measure functional MRI (fMRI) and electroencephalography (EEG) changes in absence seizures with impaired task performance compared with seizures in which performance was spared. ⋯ National Institutes of Health, National Institute of Neurological Disorders and Stroke, National Center for Advancing Translational Science, the Loughridge Williams Foundation, and the Betsy and Jonathan Blattmachr Family.
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Observational Study
Diseases associated with electrolyte imbalance in the ED: age-related differences.
The objective of the study is to investigate the prevalence of electrolyte imbalance (EI) in the emergency department (ED) with systemic diseases in different decades of life. ⋯ In our study, 13.7% of all patients showed an EI, and only 2% of cases were alone without any associated systemic disease. Most EIs are associated to other systemic diseases. The present data also depict different age-related and disease-associated prevalence patterns of EI, thus highlighting a complex clinical scenario.
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The proportion of caesarean deliveries significantly increased from 2·0% in 1978--1985 to 36·6% in 2006-2010 among Chinese pregnant women. The rate reached 55% in 2014. In this study we explored the basic demographic characteristics and preferred method of delivery of pregnant women and analysed the associated social and psychological factors. ⋯ This project was supported by the Medjaden Academy and Research Foundation for Young Scientists (grant MJR20150047). This study was also funded by the Summer Social Practice Project of the School of Public Health and Management, Chongqing Medical University.
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Many middle-aged Chinese people have experienced the Great Leap Forward Famine of 1959-61, which could have profound long-term health consequences for exposed birth cohorts. We undertook a systematic review and meta-analysis to summarise reported famine effects on long-term health. ⋯ None.