Articles: cardiac-arrest.
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Review Meta Analysis
Efficacy of vasopressin during cardio-pulmonary resuscitation in adult patients: A meta-analysis.
Experimental and animal studies suggested that vasopressin may have a favorable survival profile during CPR. This meta-analysis aimed to determine the efficacy of vasopressin in adult cardiac patients. ⋯ ROSC in "in-hospital" cardiac arrest patients is significantly better when vasopressin was used. A subgroup analysis of this meta-analysis found that ROSC, survival to hospital admission and discharge and favorable neurological outcome may be better when vasopressin was used as repeated boluses of 4-5 times titrated to desired effects; however, overall no beneficial effect was noted in unselected cardiac arrest population.
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Review Meta Analysis
Adrenaline for out-of-hospital cardiac arrest resuscitation: A systematic review and meta-analysis of randomised controlled trials.
The evidence for adrenaline in out-of-hospital cardiac arrest (OHCA) resuscitation is inconclusive. We systematically reviewed the efficacy of adrenaline for adult OHCA. ⋯ There was no benefit of adrenaline in survival to discharge or neurological outcomes. There were improved rates of survival to admission and ROSC with SDA over placebo and HDA over SDA.
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Meta Analysis Comparative Study
Compression-only cardiopulmonary resuscitation vs standard cardiopulmonary resuscitation: an updated meta-analysis of observational studies.
Survival after compression-only CPR is comparable to standard CPR if the cause of arrest is cardiac.
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Review Meta Analysis
No Benefit to Prehospital Initiation of Therapeutic Hypothermia in Out-of-hospital Cardiac Arrest: A Systematic Review and Meta-analysis.
Initiating therapeutic hypothermia for out-of-hospital cardiac arrest pre-hospital does not improve survival or neurological outcome.
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Review Meta Analysis
Audiovisual feedback device use by health care professionals during CPR: a systematic review and meta-analysis of randomised and non-randomised trials.
A systematic appraisal of the literature to determine if audiovisual feedback devices can improve CPR quality delivered by health care practitioners (HCPs) and/or survival outcomes following cardiac arrest. ⋯ In both manikin and human studies, feedback during resuscitation can result in rescuers providing CC parameters closer to recommendations. There is no evidence that this translates into improved patient outcomes. The reason for this is not yet evident and further patient centered research is warranted.