Articles: general-anesthesia.
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Randomized Controlled Trial Comparative Study Clinical Trial
General anaesthesia for caesarean section in severe pre-eclampsia. Comparison of the renal and hepatic effects of enflurane and halothane.
In a randomized study of patients undergoing Caesarean section, either enflurane (mean 0.24 MAC-h) or halothane (mean 0.23 MAC-h) and 50% nitrous oxide in oxygen were administered to women (n = 12) with severe pre-eclampsia-eclampsia and to 16 healthy pregnant patients with normal renal and hepatic function. No evidence of nephrotoxicity was found in any pre-eclamptic or normal patient. ⋯ Postoperative liver function tests showed no important changes from preoperative values, although reductive metabolites of halothane were not measured. In patients with severe pre-eclampsia there appears no contraindication to enflurane or, probably, halothane as volatile supplements during general anaesthesia.
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Comparative Study
Electromyography in anaesthesia. A comparison between two methods.
Two instruments measuring evoked compound muscle action potentials (EMG) produced by train of four stimulation of the ulnar nerve were compared. The neuromuscular transmission section of a Datex Anaesthesia and Brain Monitor (ABM), which utilises an integration technique to measure the EMG, and the Medelec MS6 , by which amplitude of the EMG was recorded and measured were attached to the same electrodes placed over adductor pollicis. ⋯ The changes in neuromuscular transmission measured by the two methods correlated well, with no statistically significant difference in results. The ABM provides a simple and accurate automatic measurement of evoked EMG for use in the study of neuromuscular transmission.
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Drug Intell Clin Pharm · Jun 1984
Case ReportsAnaphylactoid reaction caused by intravenous doxycycline during general anesthesia and beta-blockade treatment.
A 71-year-old woman with icterus was treated with doxycycline orally for one week. She then was admitted for an exploratory laparotomy under general anesthesia with barbiturate, pancuronium, fentanyl, and nitrous oxide. ⋯ Soon after the completed infusion, she developed a severe anaphylactoid reaction with bronchospasm, hypotension, and generalized urticaria, which was treated successfully with ephedrine, aminophylline, hydrocortisone, furosemide, metaraminol, ketamine, and epinephrine. The possibility of beta-blockade treatment worsening the reaction is discussed and five other reports of anaphylactoid reactions to intravenous doxycycline are mentioned.