Articles: general-anesthesia.
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The Laerdal mask can be easily modified to permit nasotracheal intubation to be undertaken under general anaesthesia with the aid of a fiberoptic laryngoscope.
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Br J Obstet Gynaecol · Jun 1980
Diazepam as an induction agent for caesarean section: a clinical and pharmacokinetic study of fetal drug exposure.
The transplacental passage and clinical effects of diazepam have been studied in 30 patients undergoing elective Caesarean section. General anaesthesia was induced with diazepam (20 mg) and maintained with nitrous oxide/oxygen. ⋯ The concentrations of diazepam in serial blood samples obtained from the mothers, the umbilical cord and the newborn infants demonstrated that the transplacental passage of the drug was rapid and there was evidence that the distribution of the drug between the mother and the fetus came close to equilibrium. There was no consistent relation between Apgar scores and the extent of the fetal exposure to diazepam.
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Acta Anaesthesiol Scand · Jun 1980
Case ReportsEar injury caused by elevated intratympanic pressure during general anaesthesia.
Two cases of middle-ear injury, due to sharp fluctuations of intratympanic pressure as a result of general anaesthesia with nitrous oxide are presented. A study is reported indicating that the degree of these fluctuations is a function of the concentration of nitrous oxide. In order to reduce the risk of middle-ear injury due to nitrous oxide anaesthesia, it is suggested that the lowest concentration feasible should be used where there is a history of previous ear surgery.
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Acta Anaesthesiol Scand · Jun 1980
Comparative StudyCyclic AMP and metabolic substrates following hemorrhage in awake and anesthetized rats.
The levels of several metabolites in plasma were studied during a period of 4 h in awake and barbiturate anesthetized rats after a blood volume loss of approximately 3% of b.w. Blood pressure was 70 mmHg (9.3 kPa) in the awake and 35 mmHg (4.7 kPa) in the anesthetized rats. Resting levels of plasma glucose, blood lactate and pyruvate and plasma cyclic AMP were higher in the awake rats than in the anesthetized rats. ⋯ The initial changes in plasma metabolite levels appeared to be directly related to changes in plasma catecholamine levels. There were no differences in the relationship between the adrenaline level and cyclic AMP or glucose increase, suggesting that anesthesia did not alter beta-adrenoceptor sensitivity, but only catecholamine concentrations. The results also indicate that awake rats tolerate long-lasting blood volume loss better than anesthetized rats, because the sympatho-adrenal activation is more short-lasting.
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The authors reviewed the records of seventy preterm infants suffering from respiratory distress syndrome and, in most cases, refractory congestive heart failure, who underwent ligation of patent ductus arteriosus. The peri-operative management of these patients is described. The anaesthetic technique consisted of nitrous oxide and oxygen supplemented with a relaxant. ⋯ The infants were protected from significant temperature fluctuations by various methods which are described. The overall survival rate of all preterm infants with respiratory distress syndrome. The management presented is considered acceptable to the infants, to the surgeons and to the anaesthetists.