Articles: chronic.
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Journal of anesthesia · Aug 2014
Randomized Controlled TrialMethadone patient-controlled analgesia for postoperative pain: a randomized, controlled, double-blind study.
Postoperative pain is an important health-care issue. Patient-controlled analgesia (PCA) is considered the gold standard for systemic postoperative pain treatment. Methadone PCA is used for patients with chronic pain and those in the palliative care setting. However, its efficacy as a first-line drug for acute postoperative pain is unknown. This study evaluated the use of postoperative methadone PCA after total hip arthroplasty (THA) compared with morphine PCA. ⋯ This study demonstrated that methadone PCA prompted less opioid consumption and lower pain scores at rest and at motion in comparison with morphine PCA as postoperative analgesia after THA.
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Headache is one of the most common symptoms after cocaine use. ⋯ Chronic cocaine use frequently seems to worsen or induce headache with migraine or migraine-like characteristics, probably owing to a serotoninergic and dopaminergic system impairment. In headache sufferers, especially those with migraine headaches, clinicians should enquire into possible cocaine use.
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A 25-year-old black man presented with left-sided chest pain and cough for 3 days. His pain was pressure-like and nonradiating and was aggravated with movement and relieved when the patient lay at a 45° angle. ⋯ He had no chronic medical conditions and was not taking medications. He had no known exposure to chemicals, fumes, or dust and no history of tobacco or alcohol abuse.
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The aim of this study was to evaluate sensitization and habituation of median somatosensory-evoked potential (MSEP) and correlate with migraine characteristics and allodynia. ⋯ The migraineurs have impaired cortical inhibition to somatosensory stimuli, and sensitization may be a feature of chronicity.