Articles: chronic.
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Bronchiectasis PostersSESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: To evaluate the effects of treatment with inhaled tobramycin in patients with non-CF bronchiectasis (BQ) considering the eradication of Pseudomona aeruginosa in sputum, changes in sputum and lung function. ⋯ The following authors have nothing to disclose: Georgina Gramblicka, María Sosa, Gabriela Tabaj, María Gallardo, Valeria Morandi, Maria Laura Grodnitzky, Luciano Peyrano, Daniela Visentini, Patricia MalamudNo Product/Research Disclosure Information.
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Reg Anesth Pain Med · Mar 2014
Case ReportsDyskinesia Caused by Ziconotide-Baclofen Combination in an Adolescent Affected by Cerebral Palsy.
To report on the first case of ziconotide-induced dyskinesia. Ziconotide, a synthetic peptide analogue of the ω-conotoxin MVIIA that blocks selectively N-type voltage-sensitive calcium channels, has been used in intrathecal administration for 30 years. Ziconotide is a drug of choice for chronic pain because of its efficacy and flexibility because it can substitute or complement other intrathecal therapies including morphine or baclofen. Whereas substantial information is available regarding its efficacy, systematic data regarding the safety of ziconotide remain scant. The adverse reactions to ziconotide described so far regard only the coordination and execution of intentional movements. ⋯ An analysis of the signaling pathways of baclofen and ziconotide revealed a possible drug interaction that allowed ziconotide to trigger dyskinesia.
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Reg Anesth Pain Med · Mar 2014
A Prospective Validation of Biplanar Ultrasound Imaging for C5-C6 Cervical Medial Branch Blocks.
Ultrasound (US) guidance offers an alternative to fluoroscopy for medial branch blocks of the upper cervical spine, but it may be less accurate for blocks at the C5 and C6 levels. We hypothesized that a modified technique using biplanar US imaging would facilitate level identification and provide greater accuracy for the lower cervical spine. ⋯ Ultrasound guidance using a biplanar approach is a reliable imaging modality for C5 and C6 medial branch blocks.
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Respiratory Support PostersSESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: Non invasive ventilation (NIV) ia a technical support in patients with acute or chronic respiratory failure. The NIV is used in patients with obesity hypoventilation syndrome (OHS) presenting with hypercapnic respiratory failure. Few studies examine the evolution and impact after starting this therapy in this patient group Objectives: To evaluate the result of non invasive ventilation started in obese patients in acute hypercapnic respiratory failure (AHRF) and its prognosis consequences. Asses the impact of long-term NIVMETHODS: Observational study with consecutive inclusion of obese patients with AHRF treated with NIV from February 2008 to June 2011. Obesity: BMI>30kg/m; AHRF: pH<7.35 and PaCO2> 45mmHg. Treatment: NIV started in general or respiratory wards and emergency department ⋯ The following authors have nothing to disclose: Concepcion Romero, Jesús Sánchez, Virginia Almadana, Ana Gómez-Bastero, Patricia Guerrero, Agustin Valido, Jose María Benítez, Teodoro MontemayorNo Product/Research Disclosure Information.
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Critical care medicine · Mar 2014
Multicenter Study Observational StudyAugmented Renal Clearance in the ICU: Results of a Multicenter Observational Study of Renal Function in Critically Ill Patients With Normal Plasma Creatinine Concentrations.
To describe the prevalence and natural history of augmented renal clearance in a cohort of recently admitted critically ill patients with normal plasma creatinine concentrations. ⋯ Augmented renal clearance appears to be a common finding in this patient group, with sustained elevation of creatinine clearance throughout the first week in ICU. Future studies should focus on the implications for accurate dosing of renally eliminated pharmaceuticals in patients with augmented renal clearance, in addition to the potential impact on individual clinical outcomes.