Articles: function.
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Numerous surveys using different techniques have been conducted in recent years to accurately classify Alzheimer's disease (AD). This research emphasized the identification of AD through neuroimaging data. However, it is important to identify symptoms as soon as possible when the disease-modifying medications function best during infection before a permanent cognitive impairment develops. ⋯ Experiments are being conducted on the Alzheimer's Neuroimaging Initiative (ADNI) dataset, and the proposed system achieves the 98.32 % accuracy level (Tab. 6, Fig. 4, Ref. 34). Text in PDF www.elis.sk. Keywords: mild cognitive impairment, deep learning, Alzheimer's disease, expected risk.
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J Coll Physicians Surg Pak · Jan 2023
Case ReportsHashimoto's Encephalopathy Presenting with Status Epilepticus and Mental Disorder as the Main Manifestations.
Hashimotos encephalopathy (HE) is an uncommon disease. It is easily misdiagnosed as many clinicians have an insufficient understanding of it. The clinical presentation, auxiliary examination, diagnosis, and treatment of a patient with HE were retrospectively analysed, and the relevant literature was reviewed and summarised. ⋯ Most patients have a good prognosis but early investigation of thyroid function and antibodies is imperative for an early and accurate diagnosis. An early treatment can greatly improve patient prognosis. Key Words: Status epilepticus, Hashimotos encephalopathy, Autoimmune disease, Mental disorder.
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Obesity and metabolic syndrome (MetS) are associated with structural and functional vascular abnormalities. MetS and its components may increase arterial stiffness and the risk of cardiovascular events. However, the relationship of MetS and its components, including obesity, with arterial stiffness is still not fully understood. ⋯ Arterial stiffness was associated with age, sex, and MetS components (BMI and FPG/T2DM). Surprisingly, the parameters of dyslipidemia do not influence stiffness parameters, which can be explained by hypolipidemic therapy. The influence of hypolipidemic therapy should therefore be borne in mind when evaluating arterial tree function (Tab. 15, Ref. 62). Text in PDF www.elis.sk Keywords: obesity, fasting plasma glucose, type 2 diabetes, aortic stiffness, metabolic syndrome, arterial hypertension, cardiovascular risk.
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During cancer surgery, the perioperative period is characterized by stress response and immunosuppression that can lead to further worsening of the disease and metastatic spread. Local anesthetics have antiproliferative, cytotoxic and antimetastatic effects on cancer cells in vitro. There is scientific evidence that local anesthetics possess anti-inflammatory effects, help to preserve normal immune function and reduce the possibility of metastatic spread. ⋯ The use of local anesthetics during the perioperative period in oncological patients may have a beneficial effect on their survival and cancer recurrence. This article summarizes the effects of local anesthetics in vitro (Tab. 1, Fig. 1, Ref. 36). Keywords: local anesthetics, cancer cells.