Articles: amnion-transplantation.
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Facial burns are common and have a significant impact on patient function and psychosocial well being. Human amnion has been used for many years as a temporary biological wound dressing in the management of partial thickness burns. The observed advantages of human amnion treatment include pain relief, ease of use, prevention of infection and acceleration of wound healing. ⋯ Superficial partial thickness facial burns can be effectively treated with dried irradiated human amnion membrane.
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Randomized Controlled Trial
Amnion in the treatment of pediatric partial-thickness facial burns.
Wound coverage for second-degree burns remains a clinical challenge. Human amniotic membranes have been used for many years in the treatment of burns; however, no large prospective clinical trials have been published. In this article, we present a novel and standardized procurement and processing method for amnion and investigate, whether the use of this biological dressing is safe and may represent a new therapeutic option for children with partial-thickness facial burns compared to standard topical treatment. ⋯ This study indicates that amnion is safe and has advantages as wound coverage for second-degree facial burns compared to the standard topical ointments. Further studies with the use of amniotic membranes on the trunk and the extremities, as well as for coverage of grafted third-degree burns, have yet to be performed.
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Comparative Study
[Fresh versus preserved amniotic membrane transplantation for conjunctival surface reconstruction].
To compare the effect of fresh versus preserved amniotic membrane transplantation for conjunctival surface reconstruction after symblepharon lysis and analyze the associated factors. ⋯ Fresh amnion has the same effect as preserved one for conjunctival surface reconstruction. The degree of symblepharon and the surgical environment of the ocular surface in the affected eye before surgery will influence the results of amniotic membrane transplantation for conjunctival surface reconstruction.
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Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi · Jul 2006
[Clinical study on application of bovine amnion on burn wounds].
To observe clinical effects of burn wounds treatment with bovine amnion and to screen the best method of preparing and storing of bovine amnion. ⋯ Bovine amnion could make benefit on burn wounds healing, reduce infection ratio of burn wounds, could be used on different kinds of burn wounds. The clinical effect between bovine amnion dealt with by glutaraldehyde and by chlorhexidine is similar. Whereas the latter is more easy to be popularized.
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Zhonghua Yan Ke Za Zhi · Feb 2004
[A clinical study of amniotic membrane transplantation for severe eye burns at the acute stage].
To investigate the possibility of ocular surface reconstruction with amniotic membrane in the acute stage of burn injury, to compare the results using fresh and preserved amniotic membranes and to evaluate the surgical methods and their effects. ⋯ Amniotic membrane transplantation (especially using a fresh membrane) can effectively reduce the inflammation of the cornea at the acute stage of burn injury, can prevent corneal ulcer and perforation and can make the stabilization process faster. It can also decrease corneal neovascularization as well as establish better conditions for successful keratoplasty.