Articles: anesthesia.
Showing all 1,825 articles tagged:
Anesthesia
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Editorial Comment
Prolonged Phrenic Nerve Blockade with Liposomal Bupivacaine.
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Editorial Comment
Does inflammation mediate behavioural alterations in anaesthesia-induced developmental neurotoxicity?
Anaesthesia exposure early in life potentially impairs neurobehavioural development. A recent study in the Journal investigated the possibility that progesterone mitigates anaesthesia-induced developmental neurotoxicity in neonatal rats exposed to sevoflurane. ⋯ The protective mechanism is proposed to relate to anti-inflammatory properties of progesterone, which brings up important questions regarding the role of inflammation in mediating the neurobehavioural alterations in anaesthesia-induced developmental neurotoxicity. We discuss this mechanism and encourage new research that may clarify the underlying mechanisms of progesterone-induced protection and extend these findings into a translational model.