Articles: dementia.
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Randomized Controlled Trial Multicenter Study
Video decision support tool for advance care planning in dementia: randomised controlled trial.
To evaluate the effect of a video decision support tool on the preferences for future medical care in older people if they develop advanced dementia, and the stability of those preferences after six weeks. ⋯ Older people who view a video depiction of a patient with advanced dementia after hearing a verbal description of the condition are more likely to opt for comfort as their goal of care compared with those who solely listen to a verbal description. They also have more stable preferences over time.
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Bmc Health Serv Res · Jan 2009
Randomized Controlled TrialDementia care initiative in primary practice: study protocol of a cluster randomized trial on dementia management in a general practice setting.
Current guidelines for dementia care recommend the combination of drug therapy with non-pharmaceutical measures like counselling and social support. However, the scientific evidence concerning non-pharmaceutical interventions for dementia patients and their informal caregivers remains inconclusive. Targets of modern comprehensive dementia care are to enable patients to live at home as long and as independent as possible and to reduce the burden of caregivers. The objective of the study is to compare a complex intervention including caregiver support groups and counselling against usual care in terms of time to nursing home placement. In this paper the study protocol is described. ⋯ From a public health perspective, the IDA trial is expected to lead to evidence based results on the community effectiveness of non-pharmaceutical support measures for dementia patients and their caregivers in the primary care sector. For health policy makers it is necessary to make their decisions about financing new services based on strong knowledge about the acceptance of measures in the population and their cost-effectiveness.
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Randomized Controlled Trial Multicenter Study
Ginkgo biloba for prevention of dementia: a randomized controlled trial.
Ginkgo biloba is widely used for its potential effects on memory and cognition. To date, adequately powered clinical trials testing the effect of G. biloba on dementia incidence are lacking. ⋯ In this study, G. biloba at 120 mg twice a day was not effective in reducing either the overall incidence rate of dementia or AD incidence in elderly individuals with normal cognition or those with MCI. Trial Registration clinicaltrials.gov Identifier: NCT00010803.
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Randomized Controlled Trial
[Effect of long-time retention of scalp needle on the abilities of cognition, daily living activity and P300 in vascular dementia patients].
To observe the curative effect of long-time retention of scalp needle in the treatment of vascular dementia (VD) patients, and its influence on P300. ⋯ Long-term retention of scalp acupuncture needles can improve VD patients' intelligence, ADL ability and EEG.
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Randomized Controlled Trial Multicenter Study
Efficacy, safety and tolerability of rivastigmine capsules in patients with probable vascular dementia: the VantagE study.
The aim was to evaluate the efficacy, safety and tolerability of rivastigmine capsules in patients diagnosed with probable vascular dementia (VaD). ⋯ VantagE (Vascular Dementia trial studying Exelon) was a 24-week, multicentre, double-blind study. VaD patients aged 50-85 years were randomized to rivastigmine capsules (3-12 mg/day) or placebo. Efficacy assessments included global and cognitive performances, activities of daily living and neuropsychiatric symptoms. Adverse events were recorded. Additional exploratory analyses determined whether heterogeneity in pathologies and symptoms extended to differential treatment effects.