Article Notes
Article pearls, summaries and comments.
I find the existence of this study perplexing. This meta-analysis appears to simply confirm basic neuromuscular pharmacology and age-related cardiovascular changes. The unanswered question is why are they so interested in using mivacurium anyway?
I conclude that good conditions for tracheal intubation are more likely when using a muscle relaxant other than mivacurium.
Despite the statistical significance of this finding, I question the clinical significance and appropriateness – especially in the context of ongoing questions regarding the safety of HES solutions and given there are alternative interventions also shown to reduce symptomatic hypotension in this setting.