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pearl
1
Epidural anesthesia may reduce post-thoracotomy chronic pain (OR 0.33) and paravertebral block reduce that following breast ca surgery (OR 0.37).
Andreae MH Andreae DA. Regional anaesthesia to prevent chronic pain after surgery: a Cochrane systematic review and meta-analysis. Br J Anaesth. 2013 Nov 1;111(5):711-20.
  Daniel Jolley
pearl
1
Maternal asthma control may be improved by multidisciplinary care, education and asthma monitoring.
Lim AS, Stewart K, Abramson MJ et al. Multidisciplinary Approach to Management of Maternal Asthma (MAMMA): A Randomized Controlled Trial. Chest. 2014 May 1;145(5):1046-54.
  Daniel Jolley
pearl
3
Greater depth of anaesthesia may be associated with a higher incidence of wound infection, mortality and composite risk of complications.
Short TG, Leslie K, Campbell D et al. A pilot study for a prospective, randomized, double-blind trial of the influence of anesthetic depth on long-term outcome. Anesth. Analg. 2014 May 1;118(5):981-6.
  Daniel Jolley
pearl
1
Videolaryngoscopic view using the C-MAC is improved when the anesthesia assistant applying cricoid pressure also has access to see the C-MAC screen.
Loughnan TE, Gunasekera E, Tan TP. Improving the C-MAC video laryngoscopic view when applying cricoid pressure by allowing access of assistant to the video screen. Anaesth Intensive Care. 2012 Jan 1;40(1):128-30.
  Daniel Jolley
pearl
1
Ultrasound-guided supraclavicular block has faster onset when a targeted intracluster-injection technique is used compared with double injection.
Techasuk W, González AP, Bernucci F et al. A randomized comparison between double-injection and targeted intracluster-injection ultrasound-guided supraclavicular brachial plexus block. Anesth. Analg. 2014 Jun 1;118(6):1363-9.
  Daniel Jolley
summary
1
Ioannidis found that earlier disproven observational studies were still positively cited in 50% or more of peer reviewed publications, despite the existence of well-established contrary evidence.
Tatsioni A, Bonitsis NG, Ioannidis JP. Persistence of contradicted claims in the literature. JAMA. 2007 Dec 5;298(21):2517-26.
  Daniel Jolley
summary
1
To explore the future contradiction of highly-cited research Ioannidis investigated just under 50 of the most significant and highly regarded medical research findings from 1990 to 2003. Of 45 that concluded their interventions were effective, 34 had had their hypothesis retested. Of these 34, over 40% (14) were subsequently shown to be incorrect or exaggerated. Forty percent of some of the most highly regarded, practice-changing medical evidence from the 20th century subsequently disproven!
Ioannidis JP. Contradicted and initially stronger effects in highly cited clinical research. JAMA. 2005 Jul 13;294(2):218-28.
  Daniel Jolley
summary
1
Ioannidis demonstrated that 80% of non-randomized studies were wrong, and among randomized controlled studies 25% were incorrect. Even large, multicenter, randomized clinical trials were predictably wrong in 10% of studies.
Ioannidis JP. Why most published research findings are false. PLoS Med. 2005 Aug 1; 2 (8): e124.
  Daniel Jolley
pearl
1
Rotating through 180^o assists intubation with a double lumen tube while reducing sore throat and vocal cord injuries.
Seo JH, Kwon TK, Jeon Y et al. Comparison of techniques for double-lumen endobronchial intubation: 90{degrees} or 180{degrees} rotation during advancement through the glottis. Br J Anaesth. 2013 Nov 1;111(5):812-7.
  Daniel Jolley
pearl
1
Use of a surgical safety checklist is associated with a reduction in all complications, and specifically with wound infection and blood loss.
Gillespie BM, Chaboyer W, Thalib L et al. Effect of Using a Safety Checklist on Patient Complications after Surgery: A Systematic Review and Meta-analysis. Anesthesiology. 2014 Jun 1;120(6):1380-9.
  Daniel Jolley