• Laura Moschettoni, Francesca Ruggiero, Filippo Maria Fava, Adolfo De Luna, and Pierpaolo Lunardi.
• Department of Neurosurgery, University of Rome "Tor Vergata", Rome, Italy. Electronic address: lauramoschettoni@gmail.com.
• World Neurosurg. 2021 Jan 1; 145: 183-186.

BackgroundEsthesioneuroblastoma (ENB) is an uncommon neuroectodermal tumor that originates from the olfactory mucosa and often recurs locally. Distant metastases of ENB have been described, but there are few reports of intramedullary metastases to the spinal cord.Case DescriptionHere we report a case of a patient presenting with a progressive paraparesis and magnetic resonance imaging findings of multiple drop metastases to thoracic and lumbar regions of the spinal cord, 17 years after diagnosis and treatment for an intracranial ENB with subsequent neck nodal metastases. The dorsal symptomatic lesion was treated with resection, radiotherapy, and adjuvant chemotherapy. The implications of spinal metastases for the clinical prognosis of this disease are discussed, with a review of the few reported cases of spinal ENB metastases in the literature.ConclusionsThrough the presentation of this case we hope to further contribute to a better understanding of this rare disease's prognosis.Copyright © 2020 Elsevier Inc. All rights reserved.

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