• Anesthesiology · Sep 2006

    Meta Analysis

    Gender and post-dural puncture headache.

    • Christopher L Wu, Andrew J Rowlingson, Seth R Cohen, Robert K Michaels, Genevieve E Courpas, Emily M Joe, and Spencer S Liu.
    • Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, MD 21287, USA. chwu@jhmi.edu
    • Anesthesiology. 2006 Sep 1; 105 (3): 613-8.

    AbstractGender is believed to be an independent risk factor for the development of post-dural puncture headache, but there are some of the inconsistencies in the available data. This systematic review examined a total of 18 trials (2,163 males, 1,917 females). The odds of developing a post-dural puncture headache were significantly lower for male than nonpregnant female subjects (odds ratio = 0.55; 95% confidence interval, 0.44-0.67). Although the authors found that nonpregnant female subjects seem to have a higher incidence of post-dural puncture headache than males, the etiology behind these findings is not clear from the current meta-analysis.

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